Allele biased transcription factor binding across human brain regions gives mechanistic insight into eQTLs

Transcription Factors (TFs) influence gene expression by facilitating or disrupting the formation of transcription initiation machinery at particular genomic loci. Because genomic localization of TFs is in part driven by TF recognition of DNA sequence, variation in TF binding sites can disrupt TF-DN...

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Detalles Bibliográficos
Autores principales: Moyers, Belle A., Loupe, Jacob M., Felker, Stephanie A., Lawlor, James M.J., Anderson, Ashlyn G., Rodriguez-Nunez, Ivan, Bunney, William E., Bunney, Blynn G., Cartagena, Preston M., Sequeira, Adolfo, Watson, Stanley J., Akil, Huda, Mendenhall, Eric M., Cooper, Gregory M., Myers, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592666/
https://www.ncbi.nlm.nih.gov/pubmed/37873117
http://dx.doi.org/10.1101/2023.10.06.561245

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