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Cell autonomous role of leucine-rich repeat kinase in protection of dopaminergic neuron survival

Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common genetic cause of Parkinson's disease (PD), which is the leading neurodegenerative movement disorder characterized by the progressive loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc). However, whe...

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Detalles Bibliográficos
Autores principales:	Kang, Jongkyun, Huang, Guodong, Ma, Long, Tong, Youren, Chen, Phoenix, Shen, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592668/ https://www.ncbi.nlm.nih.gov/pubmed/37873418 http://dx.doi.org/10.1101/2023.10.06.561293

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