Cargando…

Potential Target Discovery and Drug Repurposing for Coronaviruses: Study Involving a Knowledge Graph–Based Approach

BACKGROUND: The global pandemics of severe acute respiratory syndrome, Middle East respiratory syndrome, and COVID-19 have caused unprecedented crises for public health. Coronaviruses are constantly evolving, and it is unknown which new coronavirus will emerge and when the next coronavirus will swee...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lou, Pei, Fang, An, Zhao, Wanqing, Yao, Kuanda, Yang, Yusheng, Hu, Jiahui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	JMIR Publications 2023
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592722/ https://www.ncbi.nlm.nih.gov/pubmed/37862061 http://dx.doi.org/10.2196/45225

Ejemplares similares

Head and Tail Entity Fusion Model in Medical Knowledge Graph Construction: Case Study for Pituitary Adenoma
por: Fang, An, et al.
Publicado: (2021)

Drug repurposing for COVID-19 via knowledge graph completion
por: Zhang, Rui, et al.
Publicado: (2021)

Task-driven knowledge graph filtering improves prioritizing drugs for repurposing
por: Ratajczak, Florin, et al.
Publicado: (2022)

DrugRep-HeSiaGraph: when heterogenous siamese neural network meets knowledge graphs for drug repurposing
por: Ghorbanali, Zahra, et al.
Publicado: (2023)

A computational approach to drug repurposing using graph neural networks
por: Doshi, Siddhant, et al.
Publicado: (2022)

Biomedical knowledge graph learning for drug repurposing by extending guilt-by-association to multiple layers
por: Bang, Dongmin, et al.
Publicado: (2023)

Drug repurposing: a better approach for infectious disease drug discovery?
por: Law, G Lynn, et al.
Publicado: (2013)

Molecular-evaluated and explainable drug repurposing for COVID-19 using ensemble knowledge graph embedding
por: Islam, Md Kamrul, et al.
Publicado: (2023)

Mining on Alzheimer’s diseases related knowledge graph to identity potential AD-related semantic triples for drug repurposing
por: Nian, Yi, et al.
Publicado: (2022)

Strategies for drug repurposing against coronavirus targets
por: Smith, Poppy O., et al.
Publicado: (2021)

New opportunities for kinase drug repurposing and target discovery
por: Knapp, Stefan
Publicado: (2018)

Emerging target discovery and drug repurposing opportunities in chordoma
por: Freed, Daniel M., et al.
Publicado: (2022)

Editorial: Drug repurposing and polypharmacology: A synergistic approach in multi-target based drug discovery
por: Rudrapal, Mithun, et al.
Publicado: (2022)

A Literature-Based Knowledge Graph Embedding Method for Identifying Drug Repurposing Opportunities in Rare Diseases
por: Sosa, Daniel N., et al.
Publicado: (2020)

Discovery of new drug indications for COVID-19: A drug repurposing approach
por: Kumari, Priyanka, et al.
Publicado: (2022)

Ensembles of knowledge graph embedding models improve predictions for drug discovery
por: Rivas-Barragan, Daniel, et al.
Publicado: (2022)

Graph Theory Enables Drug Repurposing – How a Mathematical Model Can Drive the Discovery of Hidden Mechanisms of Action
por: Gramatica, Ruggero, et al.
Publicado: (2014)

Drug Repurposing: An Effective Tool in Modern Drug Discovery
por: Kulkarni, V. S., et al.
Publicado: (2023)

Toward a Coronavirus Knowledge Graph
por: Zhang, Peng, et al.
Publicado: (2021)

Fruit fly for anticancer drug discovery and repurposing
por: Nainu, Firzan, et al.
Publicado: (2023)

Adverse Drug Reaction Discovery Using a Tumor-Biomarker Knowledge Graph
por: Wang, Meng, et al.
Publicado: (2021)

A multi-targeted computational drug discovery approach for repurposing tetracyclines against monkeypox virus
por: Alandijany, Thamir A., et al.
Publicado: (2023)

Target-specific compound selectivity for multi-target drug discovery and repurposing
por: Wang, Tianduanyi, et al.
Publicado: (2022)

Drug repurposing and prediction of multiple interaction types via graph embedding
por: Amiri Souri, E., et al.
Publicado: (2023)

COVID-19: molecular targets, drug repurposing and new avenues for drug discovery
por: Senger, Mario Roberto, et al.
Publicado: (2020)

Attention-Based Aggregation Graph Networks for Knowledge Graph Information Transfer
por: Zhao, Ming, et al.
Publicado: (2020)

Drug repurposing: An effective strategy to accelerate contemporary drug discovery
por: Zhan, Peng, et al.
Publicado: (2022)

Advances in Antifungal Development: Discovery of New Drugs and Drug Repurposing
por: Kim, Jong H., et al.
Publicado: (2022)

Perspectives for repurposing drugs for the coronavirus disease 2019
por: Cherian, Sarah S., et al.
Publicado: (2020)

Repurposing old drugs as antiviral agents for coronaviruses
por: Yang, Cheng-Wei, et al.
Publicado: (2020)

Discovery and repurposing of artemisinin
por: Shi, Qiaoli, et al.
Publicado: (2022)

Repurposing Canagliflozin to target brain aging
por: Jayarathne, Hashan, et al.
Publicado: (2023)

GFCNet: Utilizing graph feature collection networks for coronavirus knowledge graph embeddings
por: Xie, Zhiwen, et al.
Publicado: (2022)

Drug Therapeutic-Use Class Prediction and Repurposing Using Graph Convolutional Networks
por: Chipofya, Mapopa, et al.
Publicado: (2021)

GCMM: graph convolution network based on multimodal attention mechanism for drug repurposing
por: Zhang, Fan, et al.
Publicado: (2022)

Editorial: Biological aspects of targeted drug discovery: Development of novel targets and/or chemotherapies, and drug repurposing
por: Kalra, Rajkumar Singh, et al.
Publicado: (2022)

Drug Repurposing: A New Hope in Drug Discovery for Prostate Cancer
por: Malik, Jonaid Ahmad, et al.
Publicado: (2022)

SemaTyP: a knowledge graph based literature mining method for drug discovery
por: Sang, Shengtian, et al.
Publicado: (2018)

Causal reasoning over knowledge graphs leveraging drug-perturbed and disease-specific transcriptomic signatures for drug discovery
por: Domingo-Fernández, Daniel, et al.
Publicado: (2022)

Topological network based drug repurposing for coronavirus 2019
por: Habibi, Mahnaz, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2u921ufb2bp1qeqc6ddp9mitd9