Nascent Chain Ubiquitination is Uncoupled from Degradation to Enable Protein Maturation

A significant proportion of nascent proteins undergo polyubiquitination on ribosomes in mammalian cells, yet the fate of these proteins remains elusive. The ribosome-associated quality control (RQC) is a mechanism that mediates the ubiquitination of nascent chains on stalled ribosomes. Here, we find...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xia, Mariappan, Malaiyalam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592752/
https://www.ncbi.nlm.nih.gov/pubmed/37873109
http://dx.doi.org/10.1101/2023.10.09.561585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592752/
https://www.ncbi.nlm.nih.gov/pubmed/37873109
http://dx.doi.org/10.1101/2023.10.09.561585

Ejemplares similares