Microbiota-dependent indole production is required for the development of collagen-induced arthritis

Altered tryptophan catabolism has been identified in inflammatory diseases like rheumatoid arthritis (RA) and spondyloarthritis (SpA), but the causal mechanisms linking tryptophan metabolites to disease are unknown. Using the collagen-induced arthritis (CIA) model we identify alterations in tryptoph...

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Detalles Bibliográficos
Autores principales: Seymour, Brenda J., Trent, Brandon, Allen, Brendan, Berlinberg, Adam J., Tangchittsumran, Jimmy, Jubair, Widian K., Chriswell, Meagan E., Liu, Sucai, Ornelas, Alfredo, Stahly, Andrew, Alexeev, Erica E., Dowdell, Alexander S., Sneed, Sunny L., Fechtner, Sabrina, Kofonow, Jennifer M., Robertson, Charles E., Dillon, Stephanie M., Wilson, Cara C., Anthony, Robert M., Frank, Daniel N., Colgan, Sean P., Kuhn, Kristine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592798/
https://www.ncbi.nlm.nih.gov/pubmed/37873395
http://dx.doi.org/10.1101/2023.10.13.561693

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