Multi-modal transcriptomic analysis unravels enrichment of hybrid epithelial/mesenchymal state and enhanced phenotypic heterogeneity in basal breast cancer

Intra-tumoral phenotypic heterogeneity promotes tumor relapse and therapeutic resistance and remains an unsolved clinical challenge. It manifests along multiple phenotypic axes and decoding the interconnections among these different axes is crucial to understand its molecular origins and to develop...

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Detalles Bibliográficos
Autores principales: Sahoo, Sarthak, Ramu, Soundharya, Nair, Madhumathy G, Pillai, Maalavika, San Juan, Beatriz P, Milioli, Heloisa Zaccaron, Mandal, Susmita, Naidu, Chandrakala M, Mavatkar, Apoorva D, Subramaniam, Harini, Neogi, Arpita G, Chaffer, Christine L, Prabhu, Jyothi S, Somarelli, Jason A, Jolly, Mohit Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592858/
https://www.ncbi.nlm.nih.gov/pubmed/37873432
http://dx.doi.org/10.1101/2023.09.30.558960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592858/
https://www.ncbi.nlm.nih.gov/pubmed/37873432
http://dx.doi.org/10.1101/2023.09.30.558960

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