Developmental conversion of thymocyte-attracting cells into self-antigen-displaying cells in embryonic thymus medulla epithelium

Thymus medulla epithelium establishes immune self-tolerance and comprises diverse cellular subsets. Functionally relevant medullary thymic epithelial cells (mTECs) include a self-antigen-displaying subset that exhibits genome-wide promiscuous gene expression promoted by the nuclear protein Aire and...

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Detalles Bibliográficos
Autores principales: Ohigashi, Izumi, White, Andrea J., Yang, Mei-Ting, Fujimori, Sayumi, Tanaka, Yu, Jacques, Alison, Kiyonari, Hiroshi, Matsushita, Yosuke, Turan, Sevilay, Kelly, Michael C., Anderson, Graham, Takahama, Yousuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592888/
https://www.ncbi.nlm.nih.gov/pubmed/37873155
http://dx.doi.org/10.1101/2023.10.03.560657

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