Sexually dimorphic mechanisms of VGLUT-mediated protection from dopaminergic neurodegeneration

Parkinson’s disease (PD) targets some dopamine (DA) neurons more than others. Sex differences offer insights, with females more protected from DA neurodegeneration. The mammalian vesicular glutamate transporter VGLUT2 and Drosophila ortholog dVGLUT have been implicated as modulators of DA neuron res...

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Detalles Bibliográficos
Autores principales: Buck, Silas A., Rubin, Sophie A., Kunkhyen, Tenzin, Treiber, Christoph D., Xue, Xiangning, Fenno, Lief E., Mabry, Samuel J., Sundar, Varun R., Yang, Zilu, Shah, Divia, Ketchesin, Kyle D., Becker-Krail, Darius D., Vasylieva, Iaroslavna, Smith, Megan C., Weisel, Florian J., Wang, Wenjia, Erickson-Oberg, M. Quincy, O’Leary, Emma I., Aravind, Eshan, Ramakrishnan, Charu, Kim, Yoon Seok, Wu, Yanying, Quick, Matthias, Coleman, Jonathan A., MacDonald, William A., Elbakri, Rania, De Miranda, Briana R., Palladino, Michael J., McCabe, Brian D., Fish, Kenneth N., Seney, Marianne L., Rayport, Stephen, Mingote, Susana, Deisseroth, Karl, Hnasko, Thomas S., Awatramani, Rajeshwar, Watson, Alan M., Waddell, Scott, Cheetham, Claire E. J., Logan, Ryan W., Freyberg, Zachary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592912/
https://www.ncbi.nlm.nih.gov/pubmed/37873436
http://dx.doi.org/10.1101/2023.10.02.560584

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