Chromatinization Modulates Topoisomerase II Processivity

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Type IIA topoisomerases are essential DNA processing enzymes that must robustly and reliably relax DNA torsional stress in vivo. While cellular processes constantly create different degrees of torsional stress, how this stress feeds back to control type IIA topoisomerase function remains obscure. Us...

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Detalles Bibliográficos
Autores principales: Lee, Jaeyoon, Wu, Meiling, Inman, James T., Singh, Gundeep, Park, Seong ha, Lee, Joyce H., Fulbright, Robert M., Hong, Yifeng, Jeong, Joshua, Berger, James M., Wang, Michelle D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592930/
https://www.ncbi.nlm.nih.gov/pubmed/37873421
http://dx.doi.org/10.1101/2023.10.03.560726
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