Cargando…

The overlapping genetic architecture of psychiatric disorders and cortical brain structure

Both psychiatric vulnerability and cortical structure are shaped by the cumulative effect of common genetic variants across the genome. However, the shared genetic underpinnings between psychiatric disorders and brain structural phenotypes, such as thickness and surface area of the cerebral cortex,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sha, Zhiqiang, Warrier, Varun, Bethlehem, Richard A.I., Schultz, Laura M., Merikangas, Alison, Sun, Kevin Y., Gur, Ruben C., Gur, Raquel E., Shinohara, Russell T., Seidlitz, Jakob, Almasy, Laura, Andreassen, Ole A., Alexander-Bloch, Aaron F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592957/ https://www.ncbi.nlm.nih.gov/pubmed/37873315 http://dx.doi.org/10.1101/2023.10.05.561040

Ejemplares similares

Robust estimation of cortical similarity networks from brain MRI
por: Sebenius, Isaac, et al.
Publicado: (2023)

Copy Number Variant Risk Scores Associated With Cognition, Psychopathology, and Brain Structure in Youths in the Philadelphia Neurodevelopmental Cohort
por: Alexander-Bloch, Aaron, et al.
Publicado: (2022)

Stability of polygenic scores across discovery genome-wide association studies
por: Schultz, Laura M., et al.
Publicado: (2022)

Genetic influences on externalizing psychopathology overlap with cognitive functioning and show developmental variation
por: Mollon, Josephine, et al.
Publicado: (2021)

Imaging local genetic influences on cortical folding
por: Alexander-Bloch, Aaron F., et al.
Publicado: (2020)

The genetic architecture of pediatric cognitive abilities in the Philadelphia Neurodevelopmental Cohort
por: Robinson, Elise B., et al.
Publicado: (2014)

Genetic risk, parental history, and suicide attempts in a diverse sample of US adolescents
por: Barzilay, Ran, et al.
Publicado: (2022)

Using the tools of genetic epidemiology to understand sex differences in neuropsychiatric disorders
por: Merikangas, Alison K., et al.
Publicado: (2020)

Quantifying the Polygenic Architecture of the Human Cerebral Cortex: Extensive Genetic Overlap between Cortical Thickness and Surface Area
por: van der Meer, Dennis, et al.
Publicado: (2020)

Synaptic and transcriptionally downregulated genes are associated with cortical thickness differences in autism
por: Romero-Garcia, Rafael, et al.
Publicado: (2018)

Grey and white matter microstructure is associated with polygenic risk for schizophrenia
por: Stauffer, Eva-Maria, et al.
Publicado: (2021)

A multi-scale cortical wiring space links cellular architecture and functional dynamics in the human brain
por: Paquola, Casey, et al.
Publicado: (2020)

The genetic architecture of the human thalamus and its overlap with ten common brain disorders
por: Elvsåshagen, Torbjørn, et al.
Publicado: (2021)

Multivariate genomic architecture of cortical thickness and surface area at multiple levels of analysis
por: Grotzinger, Andrew D., et al.
Publicado: (2023)

Modeling environment through a general exposome factor in two independent adolescent cohorts
por: Moore, Tyler M, et al.
Publicado: (2022)

Deconstructing the role of the exposome in youth suicidal ideation: Trauma, neighborhood environment, developmental and gender effects
por: Barzilay, Ran, et al.
Publicado: (2021)

A normative modelling approach reveals age-atypical cortical thickness in a subgroup of males with autism spectrum disorder
por: Bethlehem, Richard A. I., et al.
Publicado: (2020)

Identification of Novel Genomic Loci for Anxiety and Extensive Genetic Overlap with Psychiatric Disorders
por: Tesfaye, Markos, et al.
Publicado: (2023)

The genetic architecture of human cortical folding
por: van der Meer, Dennis, et al.
Publicado: (2021)

Leveraging genetic overlap between irritability and psychiatric disorders to identify genetic variants of major psychiatric disorders
por: Jung, Kyeongmin, et al.
Publicado: (2023)

Gender differences in aging: cognition, emotions, and neuroimaging studies
por: Gur, Raquel E., et al.
Publicado: (2002)

Functional magnetic resonance imaging in schizophrenia
por: Gur, Raquel E., et al.
Publicado: (2010)

Memory in health and in schizophrenia
por: Gur, Ruben C., et al.
Publicado: (2013)

Coordinated cortical thickness alterations across six neurodevelopmental and psychiatric disorders
por: Hettwer, M. D., et al.
Publicado: (2022)

What genes are differentially expressed in individuals with schizophrenia? A systematic review
por: Merikangas, Alison K., et al.
Publicado: (2022)

Two human brain systems micro-structurally associated with obesity
por: Kitzbichler, Manfred G, et al.
Publicado: (2023)

Contributions of PTSD polygenic risk and environmental stress to suicidality in preadolescents
por: Daskalakis, Nikolaos P., et al.
Publicado: (2021)

Specificity of Psychiatric Polygenic Risk Scores and Their Effects on Associated Risk Phenotypes
por: Rodrigue, Amanda L., et al.
Publicado: (2022)

Sex differences in the functional topography of association networks in youth
por: Shanmugan, Sheila, et al.
Publicado: (2022)

Regression and Alignment for Functional Data and Network Topology
por: Tu, Danni, et al.
Publicado: (2023)

A developmental reduction of the excitation:inhibition ratio in association cortex during adolescence
por: Larsen, Bart, et al.
Publicado: (2022)

A simple permutation‐based test of intermodal correspondence
por: Weinstein, Sarah M., et al.
Publicado: (2021)

Translational potential of human brain charts
por: Bedford, Saashi A., et al.
Publicado: (2022)

Microstructural and functional gradients are increasingly dissociated in transmodal cortices
por: Paquola, Casey, et al.
Publicado: (2019)

Shifts in myeloarchitecture characterise adolescent development of cortical gradients
por: Paquola, Casey, et al.
Publicado: (2019)

Genome-wide association study in 404,302 individuals identifies 7 significant loci for reaction time variability
por: Wootton, Olivia, et al.
Publicado: (2023)

Architecture and dynamics of overlapped RNA regulatory networks
por: Lapointe, Christopher P., et al.
Publicado: (2017)

Genetic Associations and Architecture of Asthma-COPD Overlap
por: John, Catherine, et al.
Publicado: (2022)

The impact of neuron morphology on cortical network architecture
por: Udvary, Daniel, et al.
Publicado: (2022)

A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework
por: LeBlanc, Marissa, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_jtijis7qk2jkg0prh1tdnqd73k