Rare variant analyses validate known ALS genes in a multi-ethnic population and identifies ANTXR2 as a candidate in PLS

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting over 30,000 people in the United States. It is characterized by the progressive decline of the nervous system that leads to the weakening of muscles which impacts physical function. Approximately, 15% of individ...

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Detalles Bibliográficos
Autores principales: Pottinger, Tess D., Motelow, Joshua E., Povysil, Gundula, Moreno, Cristiane A. Martins, Ren, Zhong, Phatnani, Hemali, Aitman, Timothy J., Santoyo-Lopez, Javier, Mitsumoto, Hiroshi, Goldstein, David B., Harms, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593055/
https://www.ncbi.nlm.nih.gov/pubmed/37873269
http://dx.doi.org/10.1101/2023.09.30.23296353

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