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Classic IgA-Vasculitis With Nephrotic Range Proteinuria - Rare Presentation in an Adult

IgA vasculitis formerly known as Henoch-Schonlein Purpura is characterized by leukocytoclastic vasculitis and IgA immune complex in small vessels of the affected organ. IgA vasculitis can involve any organ system depending upon the deposition of the IgA immune complex. IgA vasculitis is a clinical d...

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Autores principales: Teplitsky, Ella, Zafar, Maryam, Tauseef, Abubakar, Varghese, Marissa, Thirumalareddy, Joseph, Nair, Sunil, Sood, Akshat, Mirza, Mohsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Greater Baltimore Medical Center 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593165/
https://www.ncbi.nlm.nih.gov/pubmed/37877055
http://dx.doi.org/10.55729/2000-9666.1171
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author Teplitsky, Ella
Zafar, Maryam
Tauseef, Abubakar
Varghese, Marissa
Thirumalareddy, Joseph
Nair, Sunil
Sood, Akshat
Mirza, Mohsin
author_facet Teplitsky, Ella
Zafar, Maryam
Tauseef, Abubakar
Varghese, Marissa
Thirumalareddy, Joseph
Nair, Sunil
Sood, Akshat
Mirza, Mohsin
author_sort Teplitsky, Ella
collection PubMed
description IgA vasculitis formerly known as Henoch-Schonlein Purpura is characterized by leukocytoclastic vasculitis and IgA immune complex in small vessels of the affected organ. IgA vasculitis can involve any organ system depending upon the deposition of the IgA immune complex. IgA vasculitis is a clinical diagnosis which manifest with abdominal pain, arthralgia/arthritis, palpable purpura, and kidney involvement. Occasionally, serum IgA levels or skin or kidney biopsy can help in confirming the diagnosis. Treatment is usually supportive, but studies have proved that prednisone or immunosuppressive agents can help in the prevention or progression of the disease. Hereby we present a case of 54-year-old Caucasian male who developed classic tetrad findings of IgA vasculitis most likely after receiving monkeypox vaccine which patient received three weeks prior to presentation to the hospital. Kidney involvement was present but surprisingly proteinuria was above nephrotic range making it as a rare presentation of IgA vasculitis.
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spelling pubmed-105931652023-10-24 Classic IgA-Vasculitis With Nephrotic Range Proteinuria - Rare Presentation in an Adult Teplitsky, Ella Zafar, Maryam Tauseef, Abubakar Varghese, Marissa Thirumalareddy, Joseph Nair, Sunil Sood, Akshat Mirza, Mohsin J Community Hosp Intern Med Perspect Case Report IgA vasculitis formerly known as Henoch-Schonlein Purpura is characterized by leukocytoclastic vasculitis and IgA immune complex in small vessels of the affected organ. IgA vasculitis can involve any organ system depending upon the deposition of the IgA immune complex. IgA vasculitis is a clinical diagnosis which manifest with abdominal pain, arthralgia/arthritis, palpable purpura, and kidney involvement. Occasionally, serum IgA levels or skin or kidney biopsy can help in confirming the diagnosis. Treatment is usually supportive, but studies have proved that prednisone or immunosuppressive agents can help in the prevention or progression of the disease. Hereby we present a case of 54-year-old Caucasian male who developed classic tetrad findings of IgA vasculitis most likely after receiving monkeypox vaccine which patient received three weeks prior to presentation to the hospital. Kidney involvement was present but surprisingly proteinuria was above nephrotic range making it as a rare presentation of IgA vasculitis. Greater Baltimore Medical Center 2023-05-08 /pmc/articles/PMC10593165/ /pubmed/37877055 http://dx.doi.org/10.55729/2000-9666.1171 Text en © 2023 Greater Baltimore Medical Center https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ).
spellingShingle Case Report
Teplitsky, Ella
Zafar, Maryam
Tauseef, Abubakar
Varghese, Marissa
Thirumalareddy, Joseph
Nair, Sunil
Sood, Akshat
Mirza, Mohsin
Classic IgA-Vasculitis With Nephrotic Range Proteinuria - Rare Presentation in an Adult
title Classic IgA-Vasculitis With Nephrotic Range Proteinuria - Rare Presentation in an Adult
title_full Classic IgA-Vasculitis With Nephrotic Range Proteinuria - Rare Presentation in an Adult
title_fullStr Classic IgA-Vasculitis With Nephrotic Range Proteinuria - Rare Presentation in an Adult
title_full_unstemmed Classic IgA-Vasculitis With Nephrotic Range Proteinuria - Rare Presentation in an Adult
title_short Classic IgA-Vasculitis With Nephrotic Range Proteinuria - Rare Presentation in an Adult
title_sort classic iga-vasculitis with nephrotic range proteinuria - rare presentation in an adult
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593165/
https://www.ncbi.nlm.nih.gov/pubmed/37877055
http://dx.doi.org/10.55729/2000-9666.1171
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