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A human vascularized microtumor model of patient-derived colorectal cancer recapitulates clinical disease

Accurately modeling tumor biology and testing novel therapies on patient-derived cells is critically important to developing therapeutic regimens personalized to a patient’s specific disease. The vascularized microtumor (VMT), or “tumor-on-a-chip,” is a physiologic preclinical cancer model that inco...

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Detalles Bibliográficos
Autores principales: Hachey, Stephanie J., Sobrino, Agua, Lee, John G., Jafari, Mehraneh D., Klempner, Samuel J., Puttock, Eric J., Edwards, Robert A., Lowengrub, John S., Waterman, Marian L., Zell, Jason A., Hughes, Christopher C.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593408/
https://www.ncbi.nlm.nih.gov/pubmed/36481562
http://dx.doi.org/10.1016/j.trsl.2022.11.011