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The association between outdoor air pollution and body mass index, central obesity, and visceral adiposity index among middle-aged and elderly adults: a nationwide study in China

BACKGROUND: Previous animal studies have suggested that air pollution (AP) exposure may be a potential risk factor for obesity; however, there is limited epidemiological evidence available to describe the association of obesity with AP exposure. METHODS: A retrospective cross-sectional study was con...

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Autores principales: Pan, Wei, Wang, Menglong, Hu, Yingying, Lian, Zhengqi, Cheng, Haonan, Qin, Juan-Juan, Wan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593432/
https://www.ncbi.nlm.nih.gov/pubmed/37876545
http://dx.doi.org/10.3389/fendo.2023.1221325
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author Pan, Wei
Wang, Menglong
Hu, Yingying
Lian, Zhengqi
Cheng, Haonan
Qin, Juan-Juan
Wan, Jun
author_facet Pan, Wei
Wang, Menglong
Hu, Yingying
Lian, Zhengqi
Cheng, Haonan
Qin, Juan-Juan
Wan, Jun
author_sort Pan, Wei
collection PubMed
description BACKGROUND: Previous animal studies have suggested that air pollution (AP) exposure may be a potential risk factor for obesity; however, there is limited epidemiological evidence available to describe the association of obesity with AP exposure. METHODS: A retrospective cross-sectional study was conducted on 11,766 participants across mainland China in 2015. Obesity was assessed using body mass index (BMI), waist circumference (WC), and visceral adiposity index (VAI). The space-time extremely randomized tree (STET) model was used to estimate the concentration of air pollutants, including SO(2), NO(2), O(3), PM(1), PM(2.5), and PM(10), matched to participants’ residential addresses. Logistic regression models were employed to estimate the associations of obesity with outdoor AP exposure. Further stratified analysis was conducted to evaluate whether sociodemographics or lifestyles modified the effects. RESULTS: Increased AP exposure was statistically associated with increased odds of obesity. The odds ratio (ORs) and 95% confidence interval (CI) of BMI-defined obesity were 1.21 (1.17, 1.26) for SO(2), 1.33 (1.26, 1.40) for NO(2), 1.15 (1.10, 1.21) for O(3), 1.38 (1.29, 1.48) for PM(1), 1.19 (1.15, 1.22) for PM(2.5), and 1.11 (1.09, 1.13) for PM(10) per 10 μg/m(3) increase in concentration. Similar results were found for central obesity. Stratified analyses suggested that elderly participants experienced more adverse effects from all 6 air pollutants than middle-aged participants. Furthermore, notable multiplicative interactions were found between O(3) exposure and females as well as second-hand smokers in BMI-defined obesity. CONCLUSIONS: This study suggested that outdoor AP exposure had a significant association with the risk of obesity in the middle-aged and elderly Chinese population. Elderly individuals and women may be more vulnerable to AP exposure.
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spelling pubmed-105934322023-10-24 The association between outdoor air pollution and body mass index, central obesity, and visceral adiposity index among middle-aged and elderly adults: a nationwide study in China Pan, Wei Wang, Menglong Hu, Yingying Lian, Zhengqi Cheng, Haonan Qin, Juan-Juan Wan, Jun Front Endocrinol (Lausanne) Endocrinology BACKGROUND: Previous animal studies have suggested that air pollution (AP) exposure may be a potential risk factor for obesity; however, there is limited epidemiological evidence available to describe the association of obesity with AP exposure. METHODS: A retrospective cross-sectional study was conducted on 11,766 participants across mainland China in 2015. Obesity was assessed using body mass index (BMI), waist circumference (WC), and visceral adiposity index (VAI). The space-time extremely randomized tree (STET) model was used to estimate the concentration of air pollutants, including SO(2), NO(2), O(3), PM(1), PM(2.5), and PM(10), matched to participants’ residential addresses. Logistic regression models were employed to estimate the associations of obesity with outdoor AP exposure. Further stratified analysis was conducted to evaluate whether sociodemographics or lifestyles modified the effects. RESULTS: Increased AP exposure was statistically associated with increased odds of obesity. The odds ratio (ORs) and 95% confidence interval (CI) of BMI-defined obesity were 1.21 (1.17, 1.26) for SO(2), 1.33 (1.26, 1.40) for NO(2), 1.15 (1.10, 1.21) for O(3), 1.38 (1.29, 1.48) for PM(1), 1.19 (1.15, 1.22) for PM(2.5), and 1.11 (1.09, 1.13) for PM(10) per 10 μg/m(3) increase in concentration. Similar results were found for central obesity. Stratified analyses suggested that elderly participants experienced more adverse effects from all 6 air pollutants than middle-aged participants. Furthermore, notable multiplicative interactions were found between O(3) exposure and females as well as second-hand smokers in BMI-defined obesity. CONCLUSIONS: This study suggested that outdoor AP exposure had a significant association with the risk of obesity in the middle-aged and elderly Chinese population. Elderly individuals and women may be more vulnerable to AP exposure. Frontiers Media S.A. 2023-10-09 /pmc/articles/PMC10593432/ /pubmed/37876545 http://dx.doi.org/10.3389/fendo.2023.1221325 Text en Copyright © 2023 Pan, Wang, Hu, Lian, Cheng, Qin and Wan https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Pan, Wei
Wang, Menglong
Hu, Yingying
Lian, Zhengqi
Cheng, Haonan
Qin, Juan-Juan
Wan, Jun
The association between outdoor air pollution and body mass index, central obesity, and visceral adiposity index among middle-aged and elderly adults: a nationwide study in China
title The association between outdoor air pollution and body mass index, central obesity, and visceral adiposity index among middle-aged and elderly adults: a nationwide study in China
title_full The association between outdoor air pollution and body mass index, central obesity, and visceral adiposity index among middle-aged and elderly adults: a nationwide study in China
title_fullStr The association between outdoor air pollution and body mass index, central obesity, and visceral adiposity index among middle-aged and elderly adults: a nationwide study in China
title_full_unstemmed The association between outdoor air pollution and body mass index, central obesity, and visceral adiposity index among middle-aged and elderly adults: a nationwide study in China
title_short The association between outdoor air pollution and body mass index, central obesity, and visceral adiposity index among middle-aged and elderly adults: a nationwide study in China
title_sort association between outdoor air pollution and body mass index, central obesity, and visceral adiposity index among middle-aged and elderly adults: a nationwide study in china
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593432/
https://www.ncbi.nlm.nih.gov/pubmed/37876545
http://dx.doi.org/10.3389/fendo.2023.1221325
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