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Lung Cancer Classification in Histopathology Images Using Multiresolution Efficient Nets

Histopathological images are very effective for investigating the status of various biological structures and diagnosing diseases like cancer. In addition, digital histopathology increases diagnosis precision and provides better image quality and more detail for the pathologist with multiple viewing...

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Autores principales: Anjum, Sunila, Ahmed, Imran, Asif, Muhammad, Aljuaid, Hanan, Alturise, Fahad, Ghadi, Yazeed Yasin, Elhabob, Rashad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593544/
https://www.ncbi.nlm.nih.gov/pubmed/37876944
http://dx.doi.org/10.1155/2023/7282944
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author Anjum, Sunila
Ahmed, Imran
Asif, Muhammad
Aljuaid, Hanan
Alturise, Fahad
Ghadi, Yazeed Yasin
Elhabob, Rashad
author_facet Anjum, Sunila
Ahmed, Imran
Asif, Muhammad
Aljuaid, Hanan
Alturise, Fahad
Ghadi, Yazeed Yasin
Elhabob, Rashad
author_sort Anjum, Sunila
collection PubMed
description Histopathological images are very effective for investigating the status of various biological structures and diagnosing diseases like cancer. In addition, digital histopathology increases diagnosis precision and provides better image quality and more detail for the pathologist with multiple viewing options and team annotations. As a result of the benefits above, faster treatment is available, increasing therapy success rates and patient recovery and survival chances. However, the present manual examination of these images is tedious and time-consuming for pathologists. Therefore, reliable automated techniques are needed to effectively classify normal and malignant cancer images. This paper applied a deep learning approach, namely, EfficientNet and its variants from B0 to B7. We used different image resolutions for each model, from 224 × 224 pixels to 600 × 600 pixels. We also applied transfer learning and parameter tuning techniques to improve the results and overcome the overfitting problem. We collected the dataset from the Lung and Colon Cancer Histopathological Image LC25000 image dataset. The dataset acquisition consists of 25,000 histopathology images of five classes (lung adenocarcinoma, lung squamous cell carcinoma, benign lung tissue, colon adenocarcinoma, and colon benign tissue). Then, we performed preprocessing on the dataset to remove the noisy images and bring them into a standard format. The model's performance was evaluated in terms of classification accuracy and loss. We have achieved good accuracy results for all variants; however, the results of EfficientNetB2 stand excellent, with an accuracy of 97% for 260 × 260 pixels resolution images.
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spelling pubmed-105935442023-10-24 Lung Cancer Classification in Histopathology Images Using Multiresolution Efficient Nets Anjum, Sunila Ahmed, Imran Asif, Muhammad Aljuaid, Hanan Alturise, Fahad Ghadi, Yazeed Yasin Elhabob, Rashad Comput Intell Neurosci Research Article Histopathological images are very effective for investigating the status of various biological structures and diagnosing diseases like cancer. In addition, digital histopathology increases diagnosis precision and provides better image quality and more detail for the pathologist with multiple viewing options and team annotations. As a result of the benefits above, faster treatment is available, increasing therapy success rates and patient recovery and survival chances. However, the present manual examination of these images is tedious and time-consuming for pathologists. Therefore, reliable automated techniques are needed to effectively classify normal and malignant cancer images. This paper applied a deep learning approach, namely, EfficientNet and its variants from B0 to B7. We used different image resolutions for each model, from 224 × 224 pixels to 600 × 600 pixels. We also applied transfer learning and parameter tuning techniques to improve the results and overcome the overfitting problem. We collected the dataset from the Lung and Colon Cancer Histopathological Image LC25000 image dataset. The dataset acquisition consists of 25,000 histopathology images of five classes (lung adenocarcinoma, lung squamous cell carcinoma, benign lung tissue, colon adenocarcinoma, and colon benign tissue). Then, we performed preprocessing on the dataset to remove the noisy images and bring them into a standard format. The model's performance was evaluated in terms of classification accuracy and loss. We have achieved good accuracy results for all variants; however, the results of EfficientNetB2 stand excellent, with an accuracy of 97% for 260 × 260 pixels resolution images. Hindawi 2023-10-16 /pmc/articles/PMC10593544/ /pubmed/37876944 http://dx.doi.org/10.1155/2023/7282944 Text en Copyright © 2023 Sunila Anjum et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Anjum, Sunila
Ahmed, Imran
Asif, Muhammad
Aljuaid, Hanan
Alturise, Fahad
Ghadi, Yazeed Yasin
Elhabob, Rashad
Lung Cancer Classification in Histopathology Images Using Multiresolution Efficient Nets
title Lung Cancer Classification in Histopathology Images Using Multiresolution Efficient Nets
title_full Lung Cancer Classification in Histopathology Images Using Multiresolution Efficient Nets
title_fullStr Lung Cancer Classification in Histopathology Images Using Multiresolution Efficient Nets
title_full_unstemmed Lung Cancer Classification in Histopathology Images Using Multiresolution Efficient Nets
title_short Lung Cancer Classification in Histopathology Images Using Multiresolution Efficient Nets
title_sort lung cancer classification in histopathology images using multiresolution efficient nets
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593544/
https://www.ncbi.nlm.nih.gov/pubmed/37876944
http://dx.doi.org/10.1155/2023/7282944
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