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An evidenced-based diagnostic tool for superior semicircular canal dehiscence syndrome

PURPOSE: To construct a symptoms-based prediction tool to assess the likelihood of superior canal dehiscence (SSCD) on high-resolution CT. MATERIALS AND METHODS: Mathematical modeling was employed to predict radiologic evidence of SSCD at a tertiary neurotology referral center. RESULTS: A total of 1...

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Autores principales: Fritz, Christian G., Casale, Garrett G., Kana, Lulia A., Hong, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese PLA General Hospital 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593562/
https://www.ncbi.nlm.nih.gov/pubmed/37877067
http://dx.doi.org/10.1016/j.joto.2023.09.006
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author Fritz, Christian G.
Casale, Garrett G.
Kana, Lulia A.
Hong, Robert S.
author_facet Fritz, Christian G.
Casale, Garrett G.
Kana, Lulia A.
Hong, Robert S.
author_sort Fritz, Christian G.
collection PubMed
description PURPOSE: To construct a symptoms-based prediction tool to assess the likelihood of superior canal dehiscence (SSCD) on high-resolution CT. MATERIALS AND METHODS: Mathematical modeling was employed to predict radiologic evidence of SSCD at a tertiary neurotology referral center. RESULTS: A total of 168 patients were included, of which 118 had imaging-confirmed SSCD. On univariate analysis significant predictors of SSCD presence were: sound/pressure-induced vertigo (p = 0.006), disequilibrium (p = 0.008), hyperacusis (p = 0.008), and autophony (p = 0.034). Multivariate analysis enabled a 14-point symptom-weighted tool to be developed, wherein a score of ≥6 raised the suspicion of SSCD (≥70% likelihood of being present), R(2) = 0.853. CONCLUSIONS: The likelihood of SSCD on CT scan can be determined with a high degree of certainty based on symptoms recorded at presentation. Using the evidenced-based diagnostic tool validated herein, a score ≥6 with any symptom combination justifies ordering a CT scan.
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spelling pubmed-105935622023-10-24 An evidenced-based diagnostic tool for superior semicircular canal dehiscence syndrome Fritz, Christian G. Casale, Garrett G. Kana, Lulia A. Hong, Robert S. J Otol Research Article PURPOSE: To construct a symptoms-based prediction tool to assess the likelihood of superior canal dehiscence (SSCD) on high-resolution CT. MATERIALS AND METHODS: Mathematical modeling was employed to predict radiologic evidence of SSCD at a tertiary neurotology referral center. RESULTS: A total of 168 patients were included, of which 118 had imaging-confirmed SSCD. On univariate analysis significant predictors of SSCD presence were: sound/pressure-induced vertigo (p = 0.006), disequilibrium (p = 0.008), hyperacusis (p = 0.008), and autophony (p = 0.034). Multivariate analysis enabled a 14-point symptom-weighted tool to be developed, wherein a score of ≥6 raised the suspicion of SSCD (≥70% likelihood of being present), R(2) = 0.853. CONCLUSIONS: The likelihood of SSCD on CT scan can be determined with a high degree of certainty based on symptoms recorded at presentation. Using the evidenced-based diagnostic tool validated herein, a score ≥6 with any symptom combination justifies ordering a CT scan. Chinese PLA General Hospital 2023-10 2023-09-20 /pmc/articles/PMC10593562/ /pubmed/37877067 http://dx.doi.org/10.1016/j.joto.2023.09.006 Text en © 2023 PLA General Hospital Department of Otolaryngology Head and Neck Surgery. Production and hosting by Elsevier (Singapore) Pte Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Fritz, Christian G.
Casale, Garrett G.
Kana, Lulia A.
Hong, Robert S.
An evidenced-based diagnostic tool for superior semicircular canal dehiscence syndrome
title An evidenced-based diagnostic tool for superior semicircular canal dehiscence syndrome
title_full An evidenced-based diagnostic tool for superior semicircular canal dehiscence syndrome
title_fullStr An evidenced-based diagnostic tool for superior semicircular canal dehiscence syndrome
title_full_unstemmed An evidenced-based diagnostic tool for superior semicircular canal dehiscence syndrome
title_short An evidenced-based diagnostic tool for superior semicircular canal dehiscence syndrome
title_sort evidenced-based diagnostic tool for superior semicircular canal dehiscence syndrome
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593562/
https://www.ncbi.nlm.nih.gov/pubmed/37877067
http://dx.doi.org/10.1016/j.joto.2023.09.006
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