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Establishing safe high hydrostatic pressure devitalization thresholds for autologous head and neck cancer vaccination and reconstruction
High hydrostatic pressure specifically devitalizes cells and tissues without major changes in their molecular structure. Hence, high hydrostatic pressure may enhance the development of whole-cell anti-tumor vaccines, representing tumor heterogeneity and thus (neo-) antigen diversity. Moreover, safe...
Autores principales: | Maletzki, Claudia, Freiin Grote, Vivica, Kalle, Friederike, Kleitke, Thoralf, Zimpfer, Annette, Becker, Anne-Sophie, Bergmann-Ewert, Wendy, Jonitz-Heincke, Anika, Bader, Rainer, Vollmar, Brigitte, Hackenberg, Stephan, Scherzad, Agmal, Mlynski, Robert, Strüder, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593744/ https://www.ncbi.nlm.nih.gov/pubmed/37872173 http://dx.doi.org/10.1038/s41420-023-01671-z |
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