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Establishing safe high hydrostatic pressure devitalization thresholds for autologous head and neck cancer vaccination and reconstruction

High hydrostatic pressure specifically devitalizes cells and tissues without major changes in their molecular structure. Hence, high hydrostatic pressure may enhance the development of whole-cell anti-tumor vaccines, representing tumor heterogeneity and thus (neo-) antigen diversity. Moreover, safe...

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Detalles Bibliográficos
Autores principales: Maletzki, Claudia, Freiin Grote, Vivica, Kalle, Friederike, Kleitke, Thoralf, Zimpfer, Annette, Becker, Anne-Sophie, Bergmann-Ewert, Wendy, Jonitz-Heincke, Anika, Bader, Rainer, Vollmar, Brigitte, Hackenberg, Stephan, Scherzad, Agmal, Mlynski, Robert, Strüder, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593744/
https://www.ncbi.nlm.nih.gov/pubmed/37872173
http://dx.doi.org/10.1038/s41420-023-01671-z

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