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Telomouse—a mouse model with human-length telomeres generated by a single amino acid change in RTEL1

Telomeres, the ends of eukaryotic chromosomes, protect genome integrity and enable cell proliferation. Maintaining optimal telomere length in the germline and throughout life limits the risk of cancer and enables healthy aging. Telomeres in the house mouse, Mus musculus, are about five times longer...

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Detalles Bibliográficos
Autores principales:	Smoom, Riham, May, Catherine Lee, Ortiz, Vivian, Tigue, Mark, Kolev, Hannah M., Rowe, Melissa, Reizel, Yitzhak, Morgan, Ashleigh, Egyes, Nachshon, Lichtental, Dan, Skordalakes, Emmanuel, Kaestner, Klaus H., Tzfati, Yehuda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593777/ https://www.ncbi.nlm.nih.gov/pubmed/37872177 http://dx.doi.org/10.1038/s41467-023-42534-6

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