The consequences of tetraploidy on Caenorhabditis elegans physiology and sensitivity to chemotherapeutics

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Polyploid cells contain more than two copies of each chromosome. Polyploidy has important roles in development, evolution, and tissue regeneration/repair, and can arise as a programmed polyploidization event or be triggered by stress. Cancer cells are often polyploid. C. elegans nematodes are typica...

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Detalles Bibliográficos
Autores principales: Misare, Kelly R., Ampolini, Elizabeth A., Gonzalez, Hyland C., Sullivan, Kaitlan A., Li, Xin, Miller, Camille, Sosseh, Bintou, Dunne, Jaclyn B., Voelkel-Johnson, Christina, Gordon, Kacy L., Hartman, Jessica H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593782/
https://www.ncbi.nlm.nih.gov/pubmed/37872247
http://dx.doi.org/10.1038/s41598-023-45225-w
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