Cargando…

NSG1 promotes glycolytic metabolism to enhance Esophageal squamous cell carcinoma EMT process by upregulating TGF-β

As a highly enriched endosomal protein within neuronal cells, NSG1 has been discovered to facilitate the process of epithelial-mesenchymal transition (EMT) in esophageal squamous cell carcinoma (ESCC). However, the precise mechanisms behind this phenomenon have yet to be elucidated. The pivotal role...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tu, Mingshu, Yin, Xiaoqing, Zhuang, Wanzhen, Lin, Xiaoqing, Xia, Yu, Huang, Zhixin, Zheng, Yue, Huang, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593808/ https://www.ncbi.nlm.nih.gov/pubmed/37872157 http://dx.doi.org/10.1038/s41420-023-01694-6

Ejemplares similares

TGF-β1-Induced Upregulation of MALAT1 Promotes Kazakh's Esophageal Squamous Cell Carcinoma Invasion by EMT
por: Liu, Qing, et al.
Publicado: (2020)

TGF-β1-Induced Upregulation of MALAT1 Promotes Kazakh's Esophageal Squamous Cell Carcinoma Invasion by EMT: Erratum
por: Liu, Qing, et al.
Publicado: (2022)

RNF6 activates TGF-β1/c-Myb pathway to promote EMT in esophageal squamous cell carcinoma
por: Cheng, Jingge, et al.
Publicado: (2023)

Development and Evaluation of Serum CST1 Detection for Early Diagnosis of Esophageal Squamous Cell Carcinoma
por: Wang, Jianwei, et al.
Publicado: (2021)

TGF-β in developmental and fibrogenic EMTs
por: Lee, Jun Ho, et al.
Publicado: (2022)

Construction and validation of a novel IGFBP3-related signature to predict prognosis and therapeutic decision making for Hepatocellular Carcinoma
por: Chen, Jianlin, et al.
Publicado: (2023)

MiR-942-5p inhibits tumor migration and invasion through targeting CST1 in esophageal squamous cell carcinoma
por: Zhang, Liangming, et al.
Publicado: (2023)

YAP modulates TGF-β1-induced simultaneous apoptosis and EMT through upregulation of the EGF receptor
por: Liu, Yi, et al.
Publicado: (2017)

Angiotensin Inhibition, TGF-β and EMT in Cancer
por: Pallasch, Fabian Bernhard, et al.
Publicado: (2020)

Xenogeneic Graft-Versus-Host Disease in Humanized NSG and NSG-HLA-A2/HHD Mice
por: Ehx, Grégory, et al.
Publicado: (2018)

Downregulation of microRNA-4324 promotes the EMT of esophageal squamous-cell carcinoma cells via upregulating FAK
por: Zhou, Jian, et al.
Publicado: (2019)

Upregulation of long noncoding RNA HOTTIP promotes metastasis of esophageal squamous cell carcinoma via induction of EMT
por: Chen, Xuemei, et al.
Publicado: (2016)

The CERN neutrino beam to Gran Sasso: NSG
por: Weisse, E
Publicado: (1999)

The endosomal neuronal proteins Nsg1/NEEP21 and Nsg2/P19 are itinerant, not resident proteins of dendritic endosomes
por: Yap, Chan Choo, et al.
Publicado: (2017)

TGF-β-Upregulated Lnc-Nr6a1 Acts as a Reservoir of miR-181 and Mediates Assembly of a Glycolytic Complex
por: Polo-Generelo, Salvador, et al.
Publicado: (2022)

RAC1 inhibition reverses cisplatin resistance in esophageal squamous cell carcinoma and induces downregulation of glycolytic enzymes
por: Zeng, Rui‐Jie, et al.
Publicado: (2019)

Influence of age, irradiation and humanization on NSG mouse phenotypes
por: Knibbe-Hollinger, Jaclyn S., et al.
Publicado: (2015)

Demethylzelasteral inhibits proliferation and EMT via repressing Wnt/β-catenin signaling in esophageal squamous cell carcinoma
por: Yu, Jiarui, et al.
Publicado: (2021)

Organ Fibrosis and Autoimmunity: The Role of Inflammation in TGFβ-Dependent EMT
por: Sisto, Margherita, et al.
Publicado: (2021)

LAMC1 upregulation via TGFβ induces inflammatory cancer‐associated fibroblasts in esophageal squamous cell carcinoma via NF‐κB–CXCL1–STAT3
por: Fang, Lingling, et al.
Publicado: (2021)

Fractionated irradiation-induced EMT-like phenotype conferred radioresistance in esophageal squamous cell carcinoma
por: Zhang, Hongfang, et al.
Publicado: (2016)

Anti-tumor Drug THZ1 Suppresses TGFβ2-mediated EMT in Lens Epithelial Cells via Notch and TGFβ/Smad Signaling Pathway
por: Ning, Jie, et al.
Publicado: (2019)

The lncRNA CCAT1 upregulates TGFβR1 via sponging miR-490-3p to promote TGFβ1-induced EMT of ovarian cancer cells
por: Mu, Yang, et al.
Publicado: (2018)

SHCBP1 Promotes the Progression of Esophageal Squamous Cell Carcinoma Via the TGFβ Pathway
por: Ren, Chunhong, et al.
Publicado: (2021)

Tex10 promotes stemness and EMT phenotypes in esophageal squamous cell carcinoma via the Wnt/β-catenin pathway
por: Xiang, Xiaocong, et al.
Publicado: (2019)

TGFβ Drives Metabolic Perturbations during Epithelial Mesenchymal Transition in Pancreatic Cancer: TGFβ Induced EMT in PDAC
por: Rajagopal, Meena U., et al.
Publicado: (2021)

Methylation silencing of TGF-β receptor type II is involved in malignant transformation of esophageal squamous cell carcinoma
por: Ma, Yarui, et al.
Publicado: (2020)

The transcription factor LEF1 promotes tumorigenicity and activates the TGF-β signaling pathway in esophageal squamous cell carcinoma
por: Zhao, Yue, et al.
Publicado: (2019)

aV integrins and TGF-β-induced EMT: a circle of regulation
por: Mamuya, Fahmy A, et al.
Publicado: (2012)

TGF-β isoforms induce EMT independent migration of ovarian cancer cells
por: Gao, Jingfang, et al.
Publicado: (2014)

Establishment of a TGFβ-Induced Post-Transcriptional EMT Gene Signature
por: Hussey, George S., et al.
Publicado: (2012)

Signal Transduction Pathways of EMT Induced by TGF-β, SHH, and WNT and Their Crosstalks
por: Zhang, Jingyu, et al.
Publicado: (2016)

PTBP3 mediates TGF-β-induced EMT and metastasis of lung adenocarcinoma
por: Dong, Chenglai, et al.
Publicado: (2022)

MicroRNA-590 is an EMT-suppressive microRNA involved in the TGFβ signaling pathway
por: LIU, TIANMING, et al.
Publicado: (2015)

αvβ3 Integrin induces partial EMT independent of TGF-β signaling
por: Kariya, Yoshinobu, et al.
Publicado: (2021)

Estrogen attenuates TGF-β1-induced EMT in intrauterine adhesion by activating Wnt/β-catenin signaling pathway
por: Cao, Jia, et al.
Publicado: (2020)

INHBA upregulation correlates with poorer prognosis in patients with esophageal squamous cell carcinoma
por: Lyu, Shanshan, et al.
Publicado: (2018)

Oxymatrine Inhibits Renal Tubular EMT Induced by High Glucose via Upregulation of SnoN and Inhibition of TGF-β1/Smad Signaling Pathway
por: Liu, Lirong, et al.
Publicado: (2016)

lncRNA CASC9 sponges miR-758-3p to promote proliferation and EMT in bladder cancer by upregulating TGF-β2
por: Zhang, Zeng, et al.
Publicado: (2021)

Berberine Suppresses EMT in Liver and Gastric Carcinoma Cells through Combination with TGFβR Regulating TGF-β/Smad Pathway
por: Du, Haiyan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_fcbktbnhdi476rag33s4c8i35m