Cargando…

Molluscum contagiosum presenting as periorbital abscess in immunocompetent children

Molluscum contagiosum presenting as a periorbital region abscess is unusual. The virus generally causes a self-limiting localized disease in children. Presentation as an abscess has been reported mainly in immunocompromised patients. We performed a retrospective study of ten children treated for Mol...

Descripción completa

Detalles Bibliográficos
Autores principales: Mor-Shaham, Moran, Gutovitz, Joel, Levinkron, Oz, Krausz, Judit, Briscoe, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593814/
https://www.ncbi.nlm.nih.gov/pubmed/37872236
http://dx.doi.org/10.1038/s41598-023-45320-y
_version_ 1785124512814071808
author Mor-Shaham, Moran
Gutovitz, Joel
Levinkron, Oz
Krausz, Judit
Briscoe, Daniel
author_facet Mor-Shaham, Moran
Gutovitz, Joel
Levinkron, Oz
Krausz, Judit
Briscoe, Daniel
author_sort Mor-Shaham, Moran
collection PubMed
description Molluscum contagiosum presenting as a periorbital region abscess is unusual. The virus generally causes a self-limiting localized disease in children. Presentation as an abscess has been reported mainly in immunocompromised patients. We performed a retrospective study of ten children treated for Molluscum contagiosum infection presenting as periorbital abscess. Data investigated included age, immunocompetence, systemic antibiotic treatment, clinical findings, and histopathology. All children were immunocompetent. Bacterial cultures taken in six of the ten children were positive in two. Seven patients received oral antibiotics before presentation but required IV antibiotics on admission. One patient received IV antibiotics only. All antibiotic treatment had very limited effect. Two patients had no antibiotic treatment. CT imaging in one case where orbital cellulitis was suspected showed no significant intraorbital findings with anterior involvement only. Nine out of ten children had surgery and intra-operative cryotherapy at our center with immediate improvement and recovery. One child whose parents initially refused surgical excision had initial limited clinical improvement of periorbital swelling with antibiotics. However, the lesions were excised shortly following discharge from our hospital at another medical center with a complete cure. Molluscum is a cause of periorbital abscess in immunocompetent children which should be part of the differential diagnosis in periorbital/adnexal infection. Antibiotic treatment has a limited effect, and the abscess is most likely a virally triggered reaction. Surgical excision and intra-operative cryotherapy are curative of the disease in our experience.
format Online
Article
Text
id pubmed-10593814
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-105938142023-10-25 Molluscum contagiosum presenting as periorbital abscess in immunocompetent children Mor-Shaham, Moran Gutovitz, Joel Levinkron, Oz Krausz, Judit Briscoe, Daniel Sci Rep Article Molluscum contagiosum presenting as a periorbital region abscess is unusual. The virus generally causes a self-limiting localized disease in children. Presentation as an abscess has been reported mainly in immunocompromised patients. We performed a retrospective study of ten children treated for Molluscum contagiosum infection presenting as periorbital abscess. Data investigated included age, immunocompetence, systemic antibiotic treatment, clinical findings, and histopathology. All children were immunocompetent. Bacterial cultures taken in six of the ten children were positive in two. Seven patients received oral antibiotics before presentation but required IV antibiotics on admission. One patient received IV antibiotics only. All antibiotic treatment had very limited effect. Two patients had no antibiotic treatment. CT imaging in one case where orbital cellulitis was suspected showed no significant intraorbital findings with anterior involvement only. Nine out of ten children had surgery and intra-operative cryotherapy at our center with immediate improvement and recovery. One child whose parents initially refused surgical excision had initial limited clinical improvement of periorbital swelling with antibiotics. However, the lesions were excised shortly following discharge from our hospital at another medical center with a complete cure. Molluscum is a cause of periorbital abscess in immunocompetent children which should be part of the differential diagnosis in periorbital/adnexal infection. Antibiotic treatment has a limited effect, and the abscess is most likely a virally triggered reaction. Surgical excision and intra-operative cryotherapy are curative of the disease in our experience. Nature Publishing Group UK 2023-10-23 /pmc/articles/PMC10593814/ /pubmed/37872236 http://dx.doi.org/10.1038/s41598-023-45320-y Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Mor-Shaham, Moran
Gutovitz, Joel
Levinkron, Oz
Krausz, Judit
Briscoe, Daniel
Molluscum contagiosum presenting as periorbital abscess in immunocompetent children
title Molluscum contagiosum presenting as periorbital abscess in immunocompetent children
title_full Molluscum contagiosum presenting as periorbital abscess in immunocompetent children
title_fullStr Molluscum contagiosum presenting as periorbital abscess in immunocompetent children
title_full_unstemmed Molluscum contagiosum presenting as periorbital abscess in immunocompetent children
title_short Molluscum contagiosum presenting as periorbital abscess in immunocompetent children
title_sort molluscum contagiosum presenting as periorbital abscess in immunocompetent children
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593814/
https://www.ncbi.nlm.nih.gov/pubmed/37872236
http://dx.doi.org/10.1038/s41598-023-45320-y
work_keys_str_mv AT morshahammoran molluscumcontagiosumpresentingasperiorbitalabscessinimmunocompetentchildren
AT gutovitzjoel molluscumcontagiosumpresentingasperiorbitalabscessinimmunocompetentchildren
AT levinkronoz molluscumcontagiosumpresentingasperiorbitalabscessinimmunocompetentchildren
AT krauszjudit molluscumcontagiosumpresentingasperiorbitalabscessinimmunocompetentchildren
AT briscoedaniel molluscumcontagiosumpresentingasperiorbitalabscessinimmunocompetentchildren