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C-type lectin receptor 2d forms homodimers and heterodimers with TLR2 to negatively regulate IRF5-mediated antifungal immunity

Dimerization of C-type lectin receptors (CLRs) or Toll-like receptors (TLRs) can alter their ligand binding ability, thereby modulating immune responses. However, the possibilities and roles of dimerization between CLRs and TLRs remain unclear. Here we show that C-type lectin receptor-2d (CLEC2D) fo...

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Detalles Bibliográficos
Autores principales: Li, Fan, Wang, Hui, Li, Yan-Qi, Gu, Yebo, Jia, Xin-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593818/
https://www.ncbi.nlm.nih.gov/pubmed/37872182
http://dx.doi.org/10.1038/s41467-023-42216-3