The E3 ligase TRIM26 suppresses ferroptosis through catalyzing K63-linked ubiquitination of GPX4 in glioma

The selenium-containing enzyme GPX4 moonlights as a central regulator of ferroptosis, an iron-dependent, nonapoptotic form of regulated cell death caused by lipid peroxidation. Yet, little is known about the mechanisms underlying the regulation of its post-transcriptional modifications. Here, we ide...

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Detalles Bibliográficos
Autores principales: Wang, Zhangjie, Xia, Yuan, Wang, Yang, Zhu, Ruiqiu, Li, Hongbo, Liu, Yu, Shen, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593845/
https://www.ncbi.nlm.nih.gov/pubmed/37872147
http://dx.doi.org/10.1038/s41419-023-06222-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593845/
https://www.ncbi.nlm.nih.gov/pubmed/37872147
http://dx.doi.org/10.1038/s41419-023-06222-z

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