Chronic dehydration induces injury pathways in rats, but does not mimic histopathology of chronic interstitial nephritis in agricultural communities

CINAC-patients present renal proximal tubular cell lysosomal lesions which are also observed in patients experiencing calcineurin inhibitor (CNI) nephrotoxicity, suggesting that CINAC is a toxin-induced nephropathy. An alternative hypothesis advocates chronic dehydration as a major etiological facto...

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Detalles Bibliográficos
Autores principales: Schreurs, Gerd, Maudsley, Stuart, Nast, Cynthia, Praet, Marleen, Da Silva Fernandes, Sylvina, Boor, Peter, D’Haese, Patrick, De Broe, Marc E., Vervaet, Benjamin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593944/
https://www.ncbi.nlm.nih.gov/pubmed/37872220
http://dx.doi.org/10.1038/s41598-023-43567-z

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