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Attenuates reactive oxygen species: induced pyroptosis via activation of the Nrf2/HO-1 signal pathway in models of trigeminal neuralgia

In this study, we examined the impact of demyelinating and neuroinflammation on trigeminal neuralgia (TN) by utilizing models of chronic constriction injury to the infraorbital nerve (CCI). The CCI rats were treated with either VX-765 (an inhibitor of caspase-1) or a control solution of PBS/DMSO to...

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Detalles Bibliográficos
Autores principales: Liu, Mingxing, Wang, Yongyi, Li, Shengli, Hou, Xiaoqun, Li, Tong, Xu, Zhiming, Chen, Feng, Zhou, Yong, Xia, Lei, Wang, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10593956/
https://www.ncbi.nlm.nih.gov/pubmed/37872210
http://dx.doi.org/10.1038/s41598-023-44013-w

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