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Co-cultures of cerebellar slices from mice with different reelin genetic backgrounds as a model to study cortical lamination

Background: Reelin has fundamental functions in the developing and mature brain. Its absence gives rise to the Reeler phenotype in mice, the first described cerebellar mutation. In homozygous mutants missing the Reelin gene ( reln (-/-)), neurons are incapable of correctly positioning themselves in...

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Detalles Bibliográficos
Autores principales: Merighi, Adalberto, Lossi, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594056/
https://www.ncbi.nlm.nih.gov/pubmed/37881513
http://dx.doi.org/10.12688/f1000research.126787.2