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When age is not an obstacle: A case series of endoscopic transsphenoidal resection of pituitary macroadenomas in older patients

Due to the increase in life expectancy, the number of elderly patients suffering from a pituitary macroadenoma is expected to increase in the future. The endoscopic endonasal transsphenoidal (EET) approach tends to be the first choice for the treatment of pituitary macroadenomas in the general popul...

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Autores principales: Faropoulos, Konstantinos, Gioti, Ifigeneia, Georgakopoulou, Vasiliki Epameinondas, Spandidos, Demetrios A., Papalexis, Petros, Lempesis, Ioannis G., Trakas, Nikolaos, Trakas, Ilias, Anagiotos, Andreas, Fotakopoulos, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594072/
https://www.ncbi.nlm.nih.gov/pubmed/37881600
http://dx.doi.org/10.3892/br.2023.1668
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author Faropoulos, Konstantinos
Gioti, Ifigeneia
Georgakopoulou, Vasiliki Epameinondas
Spandidos, Demetrios A.
Papalexis, Petros
Lempesis, Ioannis G.
Trakas, Nikolaos
Trakas, Ilias
Anagiotos, Andreas
Fotakopoulos, George
author_facet Faropoulos, Konstantinos
Gioti, Ifigeneia
Georgakopoulou, Vasiliki Epameinondas
Spandidos, Demetrios A.
Papalexis, Petros
Lempesis, Ioannis G.
Trakas, Nikolaos
Trakas, Ilias
Anagiotos, Andreas
Fotakopoulos, George
author_sort Faropoulos, Konstantinos
collection PubMed
description Due to the increase in life expectancy, the number of elderly patients suffering from a pituitary macroadenoma is expected to increase in the future. The endoscopic endonasal transsphenoidal (EET) approach tends to be the first choice for the treatment of pituitary macroadenomas in the general population. Notwithstanding, in the geriatric population, the goals of management for this condition remain unclear. The present study retrospectively evaluated and describes the cases of 6 patients >70 years of age with a pituitary macroadenoma who were treated by a skull base team, composed of one ENT surgeon and one neurosurgeon. All the patients experienced a notable improvement in their neurological deficit, while their hormonal status also improved or at least did not deteriorate after the surgery. The EET approach appears to be a safe and effective approach for the treatment of pituitary macroadenomas in the geriatric population.
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spelling pubmed-105940722023-10-25 When age is not an obstacle: A case series of endoscopic transsphenoidal resection of pituitary macroadenomas in older patients Faropoulos, Konstantinos Gioti, Ifigeneia Georgakopoulou, Vasiliki Epameinondas Spandidos, Demetrios A. Papalexis, Petros Lempesis, Ioannis G. Trakas, Nikolaos Trakas, Ilias Anagiotos, Andreas Fotakopoulos, George Biomed Rep Case Report Due to the increase in life expectancy, the number of elderly patients suffering from a pituitary macroadenoma is expected to increase in the future. The endoscopic endonasal transsphenoidal (EET) approach tends to be the first choice for the treatment of pituitary macroadenomas in the general population. Notwithstanding, in the geriatric population, the goals of management for this condition remain unclear. The present study retrospectively evaluated and describes the cases of 6 patients >70 years of age with a pituitary macroadenoma who were treated by a skull base team, composed of one ENT surgeon and one neurosurgeon. All the patients experienced a notable improvement in their neurological deficit, while their hormonal status also improved or at least did not deteriorate after the surgery. The EET approach appears to be a safe and effective approach for the treatment of pituitary macroadenomas in the geriatric population. D.A. Spandidos 2023-10-03 /pmc/articles/PMC10594072/ /pubmed/37881600 http://dx.doi.org/10.3892/br.2023.1668 Text en Copyright: © Faropoulos et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Case Report
Faropoulos, Konstantinos
Gioti, Ifigeneia
Georgakopoulou, Vasiliki Epameinondas
Spandidos, Demetrios A.
Papalexis, Petros
Lempesis, Ioannis G.
Trakas, Nikolaos
Trakas, Ilias
Anagiotos, Andreas
Fotakopoulos, George
When age is not an obstacle: A case series of endoscopic transsphenoidal resection of pituitary macroadenomas in older patients
title When age is not an obstacle: A case series of endoscopic transsphenoidal resection of pituitary macroadenomas in older patients
title_full When age is not an obstacle: A case series of endoscopic transsphenoidal resection of pituitary macroadenomas in older patients
title_fullStr When age is not an obstacle: A case series of endoscopic transsphenoidal resection of pituitary macroadenomas in older patients
title_full_unstemmed When age is not an obstacle: A case series of endoscopic transsphenoidal resection of pituitary macroadenomas in older patients
title_short When age is not an obstacle: A case series of endoscopic transsphenoidal resection of pituitary macroadenomas in older patients
title_sort when age is not an obstacle: a case series of endoscopic transsphenoidal resection of pituitary macroadenomas in older patients
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594072/
https://www.ncbi.nlm.nih.gov/pubmed/37881600
http://dx.doi.org/10.3892/br.2023.1668
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