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Hypertension Diagnosis, Treatment, and Control in India

IMPORTANCE: Hypertension is a major cause of morbidity and mortality worldwide. Previous efforts to characterize gaps in the hypertension care continuum—including diagnosis, treatment, and control—in India did not assess district-level variation. Local data are critical for planning, implementation,...

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Autores principales: Varghese, Jithin Sam, Venkateshmurthy, Nikhil Srinivasapura, Sudharsanan, Nikkil, Jeemon, Panniyammakal, Patel, Shivani A., Thirumurthy, Harsha, Roy, Ambuj, Tandon, Nikhil, Narayan, K. M. Venkat, Prabhakaran, Dorairaj, Ali, Mohammed K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594142/
https://www.ncbi.nlm.nih.gov/pubmed/37870834
http://dx.doi.org/10.1001/jamanetworkopen.2023.39098
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author Varghese, Jithin Sam
Venkateshmurthy, Nikhil Srinivasapura
Sudharsanan, Nikkil
Jeemon, Panniyammakal
Patel, Shivani A.
Thirumurthy, Harsha
Roy, Ambuj
Tandon, Nikhil
Narayan, K. M. Venkat
Prabhakaran, Dorairaj
Ali, Mohammed K.
author_facet Varghese, Jithin Sam
Venkateshmurthy, Nikhil Srinivasapura
Sudharsanan, Nikkil
Jeemon, Panniyammakal
Patel, Shivani A.
Thirumurthy, Harsha
Roy, Ambuj
Tandon, Nikhil
Narayan, K. M. Venkat
Prabhakaran, Dorairaj
Ali, Mohammed K.
author_sort Varghese, Jithin Sam
collection PubMed
description IMPORTANCE: Hypertension is a major cause of morbidity and mortality worldwide. Previous efforts to characterize gaps in the hypertension care continuum—including diagnosis, treatment, and control—in India did not assess district-level variation. Local data are critical for planning, implementation, and monitoring efforts to curb the burden of hypertension. OBJECTIVE: To examine the hypertension care continuum in India among individuals aged 18 to 98 years. DESIGN, SETTING, AND PARTICIPANTS: The nationally representative Fifth National Family Health Survey study was conducted in 2 phases from June 17, 2019, to March 21, 2020, and from November 21, 2020, to April 30, 2021, among 1 895 297 individuals in 28 states, 8 union territories, and 707 districts of India. EXPOSURES: District and state of residence, urban classification, age (18-39, 40-64, and ≥65 years), sex, and household wealth quintile. MAIN OUTCOMES AND MEASURES: Hypertension was defined as a self-reported diagnosis or a newly measured blood pressure of 140/90 mm Hg or more. The proportion of individuals diagnosed (self-reported), the proportion of individuals treated among those diagnosed (self-reported medication use), and the proportion of individuals with blood pressure control among those treated (blood pressure <140/90 mm Hg [aged 18-79 years] or <150/90 mm Hg [aged ≥80 years]) were calculated based on national guidelines. Age-standardized estimates of treatment and control were also provided among the total with hypertension. To assess differences in the care continuum between or within states (ie, between districts), the variance was partitioned using generalized linear mixed models. RESULTS: Of the 1 691 036 adult respondents (52.6% women; mean [SD] age, 41.6 [16.5] years), 28.1% (95% CI, 27.9%-28.3%) had hypertension, of whom 36.9% (95% CI, 36.4%-37.3%) received a diagnosis. Among those who received a diagnosis, 44.7% (95% CI, 44.1%-45.3%) reported taking medication (corresponding to 17.7% [95% CI, 17.5%-17.9%] of the total with hypertension). Among those treated, 52.5% (95% CI, 51.7%-53.4%) had blood pressure control (corresponding to 8.5% [95% CI, 8.3%-8.6%] of the total with hypertension). There were substantial variations across districts in blood pressure diagnosis (range, 6.3%-77.5%), treatment (range, 8.7%-97.1%), and control (range, 2.7%-76.6%). Large proportions of the variation in hypertension diagnosis (94.7%), treatment (93.6%), and control (97.3%) were within states, not just between states. CONCLUSIONS AND RELEVANCE: In this cross-sectional survey study of Indian adults, more than 1 in 4 people had hypertension, and of these, only 1 in 3 received a diagnosis, less than 1 in 5 were treated, and only 1 in 12 had blood pressure control. National mean values hide considerable state-level and district-level variation in the care continuum, suggesting the need for targeted, decentralized solutions to improve the hypertension care continuum in India.
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spelling pubmed-105941422023-10-25 Hypertension Diagnosis, Treatment, and Control in India Varghese, Jithin Sam Venkateshmurthy, Nikhil Srinivasapura Sudharsanan, Nikkil Jeemon, Panniyammakal Patel, Shivani A. Thirumurthy, Harsha Roy, Ambuj Tandon, Nikhil Narayan, K. M. Venkat Prabhakaran, Dorairaj Ali, Mohammed K. JAMA Netw Open Original Investigation IMPORTANCE: Hypertension is a major cause of morbidity and mortality worldwide. Previous efforts to characterize gaps in the hypertension care continuum—including diagnosis, treatment, and control—in India did not assess district-level variation. Local data are critical for planning, implementation, and monitoring efforts to curb the burden of hypertension. OBJECTIVE: To examine the hypertension care continuum in India among individuals aged 18 to 98 years. DESIGN, SETTING, AND PARTICIPANTS: The nationally representative Fifth National Family Health Survey study was conducted in 2 phases from June 17, 2019, to March 21, 2020, and from November 21, 2020, to April 30, 2021, among 1 895 297 individuals in 28 states, 8 union territories, and 707 districts of India. EXPOSURES: District and state of residence, urban classification, age (18-39, 40-64, and ≥65 years), sex, and household wealth quintile. MAIN OUTCOMES AND MEASURES: Hypertension was defined as a self-reported diagnosis or a newly measured blood pressure of 140/90 mm Hg or more. The proportion of individuals diagnosed (self-reported), the proportion of individuals treated among those diagnosed (self-reported medication use), and the proportion of individuals with blood pressure control among those treated (blood pressure <140/90 mm Hg [aged 18-79 years] or <150/90 mm Hg [aged ≥80 years]) were calculated based on national guidelines. Age-standardized estimates of treatment and control were also provided among the total with hypertension. To assess differences in the care continuum between or within states (ie, between districts), the variance was partitioned using generalized linear mixed models. RESULTS: Of the 1 691 036 adult respondents (52.6% women; mean [SD] age, 41.6 [16.5] years), 28.1% (95% CI, 27.9%-28.3%) had hypertension, of whom 36.9% (95% CI, 36.4%-37.3%) received a diagnosis. Among those who received a diagnosis, 44.7% (95% CI, 44.1%-45.3%) reported taking medication (corresponding to 17.7% [95% CI, 17.5%-17.9%] of the total with hypertension). Among those treated, 52.5% (95% CI, 51.7%-53.4%) had blood pressure control (corresponding to 8.5% [95% CI, 8.3%-8.6%] of the total with hypertension). There were substantial variations across districts in blood pressure diagnosis (range, 6.3%-77.5%), treatment (range, 8.7%-97.1%), and control (range, 2.7%-76.6%). Large proportions of the variation in hypertension diagnosis (94.7%), treatment (93.6%), and control (97.3%) were within states, not just between states. CONCLUSIONS AND RELEVANCE: In this cross-sectional survey study of Indian adults, more than 1 in 4 people had hypertension, and of these, only 1 in 3 received a diagnosis, less than 1 in 5 were treated, and only 1 in 12 had blood pressure control. National mean values hide considerable state-level and district-level variation in the care continuum, suggesting the need for targeted, decentralized solutions to improve the hypertension care continuum in India. American Medical Association 2023-10-23 /pmc/articles/PMC10594142/ /pubmed/37870834 http://dx.doi.org/10.1001/jamanetworkopen.2023.39098 Text en Copyright 2023 Varghese JS et al. JAMA Network Open. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the CC-BY License.
spellingShingle Original Investigation
Varghese, Jithin Sam
Venkateshmurthy, Nikhil Srinivasapura
Sudharsanan, Nikkil
Jeemon, Panniyammakal
Patel, Shivani A.
Thirumurthy, Harsha
Roy, Ambuj
Tandon, Nikhil
Narayan, K. M. Venkat
Prabhakaran, Dorairaj
Ali, Mohammed K.
Hypertension Diagnosis, Treatment, and Control in India
title Hypertension Diagnosis, Treatment, and Control in India
title_full Hypertension Diagnosis, Treatment, and Control in India
title_fullStr Hypertension Diagnosis, Treatment, and Control in India
title_full_unstemmed Hypertension Diagnosis, Treatment, and Control in India
title_short Hypertension Diagnosis, Treatment, and Control in India
title_sort hypertension diagnosis, treatment, and control in india
topic Original Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594142/
https://www.ncbi.nlm.nih.gov/pubmed/37870834
http://dx.doi.org/10.1001/jamanetworkopen.2023.39098
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