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Health Risks from Intake and Contact with Toxic Metal-Contaminated Water from Pager River, Uganda

Pollution of water resources is one of the major impediments to the realization of Sustainable Development Goals, especially in developing countries. The aim of this study was to investigate the physicochemical quality and potentially toxic element (lead and cadmium) concentrations in surface water...

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Autores principales: Onen, Patrick, Akemkwene, Robin, Nakiguli, Caroline K., Nimusiima, Daniel, Ruma, Daniel Hendry, Khanakwa, Alice V., Angiro, Christopher, Bamanya, Gadson, Opio, Boniface, Gonzaga, Allan, Omara, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594420/
https://www.ncbi.nlm.nih.gov/pubmed/37873812
http://dx.doi.org/10.3390/jox13040035
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author Onen, Patrick
Akemkwene, Robin
Nakiguli, Caroline K.
Nimusiima, Daniel
Ruma, Daniel Hendry
Khanakwa, Alice V.
Angiro, Christopher
Bamanya, Gadson
Opio, Boniface
Gonzaga, Allan
Omara, Timothy
author_facet Onen, Patrick
Akemkwene, Robin
Nakiguli, Caroline K.
Nimusiima, Daniel
Ruma, Daniel Hendry
Khanakwa, Alice V.
Angiro, Christopher
Bamanya, Gadson
Opio, Boniface
Gonzaga, Allan
Omara, Timothy
author_sort Onen, Patrick
collection PubMed
description Pollution of water resources is one of the major impediments to the realization of Sustainable Development Goals, especially in developing countries. The aim of this study was to investigate the physicochemical quality and potentially toxic element (lead and cadmium) concentrations in surface water sampled from Pager River, a tributary of the Nile River in Northern Uganda. Water samples (n = 18) were taken from six different points upstream (A, B, and C) and downstream (D, E, and F) of the river and analyzed following standard methods for their physiochemical properties. Atomic absorption spectroscopy was used to quantify lead and cadmium concentrations. Human health risks from ingestion and dermal contact with potentially toxic metal-contaminated water were calculated. The results obtained indicated that the mean temperature (27.7 ± 0.5–29.5 ± 0.8 °C), turbidity (40.7 ± 2.1–50.1 ± 1.1 NTU), lead (0.296 ± 0.030–0.576 ± 0.163 mg/L) and cadmium (0.278 ± 0.040–0.524 ± 0.040 mg/L) occurred at levels that surpassed their permissible limits as per World Health Organization guidelines for drinking water. Human health risk assessment showed that there are potential non-cancer risks from the ingestion of water from Pager River by adults, as the total hazard quotients were greater than one. These results emphasize the urgency to restrict the dumping of wastes into the river to minimize chances of impacting the Nile River, which flows northwards to the Mediterranean Sea. Further studies should perform routine monitoring of the river during both dry and wet seasons to establish the spatiotemporal variations of physicochemical, microbial, and trace metal profiles of the river and the associated health risks.
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spelling pubmed-105944202023-10-25 Health Risks from Intake and Contact with Toxic Metal-Contaminated Water from Pager River, Uganda Onen, Patrick Akemkwene, Robin Nakiguli, Caroline K. Nimusiima, Daniel Ruma, Daniel Hendry Khanakwa, Alice V. Angiro, Christopher Bamanya, Gadson Opio, Boniface Gonzaga, Allan Omara, Timothy J Xenobiot Article Pollution of water resources is one of the major impediments to the realization of Sustainable Development Goals, especially in developing countries. The aim of this study was to investigate the physicochemical quality and potentially toxic element (lead and cadmium) concentrations in surface water sampled from Pager River, a tributary of the Nile River in Northern Uganda. Water samples (n = 18) were taken from six different points upstream (A, B, and C) and downstream (D, E, and F) of the river and analyzed following standard methods for their physiochemical properties. Atomic absorption spectroscopy was used to quantify lead and cadmium concentrations. Human health risks from ingestion and dermal contact with potentially toxic metal-contaminated water were calculated. The results obtained indicated that the mean temperature (27.7 ± 0.5–29.5 ± 0.8 °C), turbidity (40.7 ± 2.1–50.1 ± 1.1 NTU), lead (0.296 ± 0.030–0.576 ± 0.163 mg/L) and cadmium (0.278 ± 0.040–0.524 ± 0.040 mg/L) occurred at levels that surpassed their permissible limits as per World Health Organization guidelines for drinking water. Human health risk assessment showed that there are potential non-cancer risks from the ingestion of water from Pager River by adults, as the total hazard quotients were greater than one. These results emphasize the urgency to restrict the dumping of wastes into the river to minimize chances of impacting the Nile River, which flows northwards to the Mediterranean Sea. Further studies should perform routine monitoring of the river during both dry and wet seasons to establish the spatiotemporal variations of physicochemical, microbial, and trace metal profiles of the river and the associated health risks. MDPI 2023-09-26 /pmc/articles/PMC10594420/ /pubmed/37873812 http://dx.doi.org/10.3390/jox13040035 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Onen, Patrick
Akemkwene, Robin
Nakiguli, Caroline K.
Nimusiima, Daniel
Ruma, Daniel Hendry
Khanakwa, Alice V.
Angiro, Christopher
Bamanya, Gadson
Opio, Boniface
Gonzaga, Allan
Omara, Timothy
Health Risks from Intake and Contact with Toxic Metal-Contaminated Water from Pager River, Uganda
title Health Risks from Intake and Contact with Toxic Metal-Contaminated Water from Pager River, Uganda
title_full Health Risks from Intake and Contact with Toxic Metal-Contaminated Water from Pager River, Uganda
title_fullStr Health Risks from Intake and Contact with Toxic Metal-Contaminated Water from Pager River, Uganda
title_full_unstemmed Health Risks from Intake and Contact with Toxic Metal-Contaminated Water from Pager River, Uganda
title_short Health Risks from Intake and Contact with Toxic Metal-Contaminated Water from Pager River, Uganda
title_sort health risks from intake and contact with toxic metal-contaminated water from pager river, uganda
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594420/
https://www.ncbi.nlm.nih.gov/pubmed/37873812
http://dx.doi.org/10.3390/jox13040035
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