Cargando…

Mature Triphyllic Cystic Teratoma of the Posterior Mediastinum in a Fetus: A Case Report and Literature Review

A teratoma is a neoplasm composed of cell populations or tissues that are reminiscent, in their appearance, of normal elements derived from at least two embryonic layers. Fetal mature teratomas are normally benign, cystic, and typically occur along the midline, while they are rare in the posterior m...

Descripción completa

Detalles Bibliográficos
Autores principales: Salzillo, Cecilia, Quaranta, Andrea, De Biasi, Giovanni, Cazzato, Gerardo, Serio, Gabriella, Vimercati, Antonella, Nicolì, Pierpaolo, Resta, Leonardo, Marzullo, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594467/
https://www.ncbi.nlm.nih.gov/pubmed/37873788
http://dx.doi.org/10.3390/diseases11040144
_version_ 1785124656794042368
author Salzillo, Cecilia
Quaranta, Andrea
De Biasi, Giovanni
Cazzato, Gerardo
Serio, Gabriella
Vimercati, Antonella
Nicolì, Pierpaolo
Resta, Leonardo
Marzullo, Andrea
author_facet Salzillo, Cecilia
Quaranta, Andrea
De Biasi, Giovanni
Cazzato, Gerardo
Serio, Gabriella
Vimercati, Antonella
Nicolì, Pierpaolo
Resta, Leonardo
Marzullo, Andrea
author_sort Salzillo, Cecilia
collection PubMed
description A teratoma is a neoplasm composed of cell populations or tissues that are reminiscent, in their appearance, of normal elements derived from at least two embryonic layers. Fetal mature teratomas are normally benign, cystic, and typically occur along the midline, while they are rare in the posterior mediastinum. Teratomas are frequently solitary; however, they may sometimes be associated with other congenital anomalies and/or with chromosomal abnormalities. Clinically, they are often asymptomatic but can occasionally cause compression symptoms. Prenatal diagnoses are uncommon and made with ultrasonography; differential diagnosis with other congenital conditions is mandatory. We report the case of a 21 weeks of gestational age old fetus with a mature triphyllic fetal cystic teratoma, grade 0, located in the right posterior mediastinum. The tumor presented as a 3 cm wide cystic mass that caused a contralateral shift of the surrounding structures. Histological examination later revealed the presence of derivatives of the three germ layers, such as hyaline cartilage, smooth muscle, nervous tissue, and a respiratory-type epithelium.
format Online
Article
Text
id pubmed-10594467
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-105944672023-10-25 Mature Triphyllic Cystic Teratoma of the Posterior Mediastinum in a Fetus: A Case Report and Literature Review Salzillo, Cecilia Quaranta, Andrea De Biasi, Giovanni Cazzato, Gerardo Serio, Gabriella Vimercati, Antonella Nicolì, Pierpaolo Resta, Leonardo Marzullo, Andrea Diseases Case Report A teratoma is a neoplasm composed of cell populations or tissues that are reminiscent, in their appearance, of normal elements derived from at least two embryonic layers. Fetal mature teratomas are normally benign, cystic, and typically occur along the midline, while they are rare in the posterior mediastinum. Teratomas are frequently solitary; however, they may sometimes be associated with other congenital anomalies and/or with chromosomal abnormalities. Clinically, they are often asymptomatic but can occasionally cause compression symptoms. Prenatal diagnoses are uncommon and made with ultrasonography; differential diagnosis with other congenital conditions is mandatory. We report the case of a 21 weeks of gestational age old fetus with a mature triphyllic fetal cystic teratoma, grade 0, located in the right posterior mediastinum. The tumor presented as a 3 cm wide cystic mass that caused a contralateral shift of the surrounding structures. Histological examination later revealed the presence of derivatives of the three germ layers, such as hyaline cartilage, smooth muscle, nervous tissue, and a respiratory-type epithelium. MDPI 2023-10-18 /pmc/articles/PMC10594467/ /pubmed/37873788 http://dx.doi.org/10.3390/diseases11040144 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Salzillo, Cecilia
Quaranta, Andrea
De Biasi, Giovanni
Cazzato, Gerardo
Serio, Gabriella
Vimercati, Antonella
Nicolì, Pierpaolo
Resta, Leonardo
Marzullo, Andrea
Mature Triphyllic Cystic Teratoma of the Posterior Mediastinum in a Fetus: A Case Report and Literature Review
title Mature Triphyllic Cystic Teratoma of the Posterior Mediastinum in a Fetus: A Case Report and Literature Review
title_full Mature Triphyllic Cystic Teratoma of the Posterior Mediastinum in a Fetus: A Case Report and Literature Review
title_fullStr Mature Triphyllic Cystic Teratoma of the Posterior Mediastinum in a Fetus: A Case Report and Literature Review
title_full_unstemmed Mature Triphyllic Cystic Teratoma of the Posterior Mediastinum in a Fetus: A Case Report and Literature Review
title_short Mature Triphyllic Cystic Teratoma of the Posterior Mediastinum in a Fetus: A Case Report and Literature Review
title_sort mature triphyllic cystic teratoma of the posterior mediastinum in a fetus: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594467/
https://www.ncbi.nlm.nih.gov/pubmed/37873788
http://dx.doi.org/10.3390/diseases11040144
work_keys_str_mv AT salzillocecilia maturetriphylliccysticteratomaoftheposteriormediastinuminafetusacasereportandliteraturereview
AT quarantaandrea maturetriphylliccysticteratomaoftheposteriormediastinuminafetusacasereportandliteraturereview
AT debiasigiovanni maturetriphylliccysticteratomaoftheposteriormediastinuminafetusacasereportandliteraturereview
AT cazzatogerardo maturetriphylliccysticteratomaoftheposteriormediastinuminafetusacasereportandliteraturereview
AT seriogabriella maturetriphylliccysticteratomaoftheposteriormediastinuminafetusacasereportandliteraturereview
AT vimercatiantonella maturetriphylliccysticteratomaoftheposteriormediastinuminafetusacasereportandliteraturereview
AT nicolipierpaolo maturetriphylliccysticteratomaoftheposteriormediastinuminafetusacasereportandliteraturereview
AT restaleonardo maturetriphylliccysticteratomaoftheposteriormediastinuminafetusacasereportandliteraturereview
AT marzulloandrea maturetriphylliccysticteratomaoftheposteriormediastinuminafetusacasereportandliteraturereview