Cargando…
Mature Triphyllic Cystic Teratoma of the Posterior Mediastinum in a Fetus: A Case Report and Literature Review
A teratoma is a neoplasm composed of cell populations or tissues that are reminiscent, in their appearance, of normal elements derived from at least two embryonic layers. Fetal mature teratomas are normally benign, cystic, and typically occur along the midline, while they are rare in the posterior m...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594467/ https://www.ncbi.nlm.nih.gov/pubmed/37873788 http://dx.doi.org/10.3390/diseases11040144 |
_version_ | 1785124656794042368 |
---|---|
author | Salzillo, Cecilia Quaranta, Andrea De Biasi, Giovanni Cazzato, Gerardo Serio, Gabriella Vimercati, Antonella Nicolì, Pierpaolo Resta, Leonardo Marzullo, Andrea |
author_facet | Salzillo, Cecilia Quaranta, Andrea De Biasi, Giovanni Cazzato, Gerardo Serio, Gabriella Vimercati, Antonella Nicolì, Pierpaolo Resta, Leonardo Marzullo, Andrea |
author_sort | Salzillo, Cecilia |
collection | PubMed |
description | A teratoma is a neoplasm composed of cell populations or tissues that are reminiscent, in their appearance, of normal elements derived from at least two embryonic layers. Fetal mature teratomas are normally benign, cystic, and typically occur along the midline, while they are rare in the posterior mediastinum. Teratomas are frequently solitary; however, they may sometimes be associated with other congenital anomalies and/or with chromosomal abnormalities. Clinically, they are often asymptomatic but can occasionally cause compression symptoms. Prenatal diagnoses are uncommon and made with ultrasonography; differential diagnosis with other congenital conditions is mandatory. We report the case of a 21 weeks of gestational age old fetus with a mature triphyllic fetal cystic teratoma, grade 0, located in the right posterior mediastinum. The tumor presented as a 3 cm wide cystic mass that caused a contralateral shift of the surrounding structures. Histological examination later revealed the presence of derivatives of the three germ layers, such as hyaline cartilage, smooth muscle, nervous tissue, and a respiratory-type epithelium. |
format | Online Article Text |
id | pubmed-10594467 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-105944672023-10-25 Mature Triphyllic Cystic Teratoma of the Posterior Mediastinum in a Fetus: A Case Report and Literature Review Salzillo, Cecilia Quaranta, Andrea De Biasi, Giovanni Cazzato, Gerardo Serio, Gabriella Vimercati, Antonella Nicolì, Pierpaolo Resta, Leonardo Marzullo, Andrea Diseases Case Report A teratoma is a neoplasm composed of cell populations or tissues that are reminiscent, in their appearance, of normal elements derived from at least two embryonic layers. Fetal mature teratomas are normally benign, cystic, and typically occur along the midline, while they are rare in the posterior mediastinum. Teratomas are frequently solitary; however, they may sometimes be associated with other congenital anomalies and/or with chromosomal abnormalities. Clinically, they are often asymptomatic but can occasionally cause compression symptoms. Prenatal diagnoses are uncommon and made with ultrasonography; differential diagnosis with other congenital conditions is mandatory. We report the case of a 21 weeks of gestational age old fetus with a mature triphyllic fetal cystic teratoma, grade 0, located in the right posterior mediastinum. The tumor presented as a 3 cm wide cystic mass that caused a contralateral shift of the surrounding structures. Histological examination later revealed the presence of derivatives of the three germ layers, such as hyaline cartilage, smooth muscle, nervous tissue, and a respiratory-type epithelium. MDPI 2023-10-18 /pmc/articles/PMC10594467/ /pubmed/37873788 http://dx.doi.org/10.3390/diseases11040144 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Salzillo, Cecilia Quaranta, Andrea De Biasi, Giovanni Cazzato, Gerardo Serio, Gabriella Vimercati, Antonella Nicolì, Pierpaolo Resta, Leonardo Marzullo, Andrea Mature Triphyllic Cystic Teratoma of the Posterior Mediastinum in a Fetus: A Case Report and Literature Review |
title | Mature Triphyllic Cystic Teratoma of the Posterior Mediastinum in a Fetus: A Case Report and Literature Review |
title_full | Mature Triphyllic Cystic Teratoma of the Posterior Mediastinum in a Fetus: A Case Report and Literature Review |
title_fullStr | Mature Triphyllic Cystic Teratoma of the Posterior Mediastinum in a Fetus: A Case Report and Literature Review |
title_full_unstemmed | Mature Triphyllic Cystic Teratoma of the Posterior Mediastinum in a Fetus: A Case Report and Literature Review |
title_short | Mature Triphyllic Cystic Teratoma of the Posterior Mediastinum in a Fetus: A Case Report and Literature Review |
title_sort | mature triphyllic cystic teratoma of the posterior mediastinum in a fetus: a case report and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594467/ https://www.ncbi.nlm.nih.gov/pubmed/37873788 http://dx.doi.org/10.3390/diseases11040144 |
work_keys_str_mv | AT salzillocecilia maturetriphylliccysticteratomaoftheposteriormediastinuminafetusacasereportandliteraturereview AT quarantaandrea maturetriphylliccysticteratomaoftheposteriormediastinuminafetusacasereportandliteraturereview AT debiasigiovanni maturetriphylliccysticteratomaoftheposteriormediastinuminafetusacasereportandliteraturereview AT cazzatogerardo maturetriphylliccysticteratomaoftheposteriormediastinuminafetusacasereportandliteraturereview AT seriogabriella maturetriphylliccysticteratomaoftheposteriormediastinuminafetusacasereportandliteraturereview AT vimercatiantonella maturetriphylliccysticteratomaoftheposteriormediastinuminafetusacasereportandliteraturereview AT nicolipierpaolo maturetriphylliccysticteratomaoftheposteriormediastinuminafetusacasereportandliteraturereview AT restaleonardo maturetriphylliccysticteratomaoftheposteriormediastinuminafetusacasereportandliteraturereview AT marzulloandrea maturetriphylliccysticteratomaoftheposteriormediastinuminafetusacasereportandliteraturereview |