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Protein interaction network analysis of mTOR signaling reveals modular organization

The mammalian target of rapamycin (mTOR) is a serine-threonine kinase that acts as a central mediator of translation and plays important roles in cell growth, synaptic plasticity, cancer, and a wide range of developmental disorders. The signaling cascade linking lipid kinases (phosphoinositide 3-kin...

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Detalles Bibliográficos
Autores principales: Wehle, Devin T., Bass, Carter S., Sulc, Josef, Mirzaa, Ghayda, Smith, Stephen E.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594569/
https://www.ncbi.nlm.nih.gov/pubmed/37741456
http://dx.doi.org/10.1016/j.jbc.2023.105271