Cargando…
NRF2/ARE mediated antioxidant response to glaucoma: role of glia and retinal ganglion cells
Glaucoma, the second leading cause of irreversible blindness worldwide, is associated with age and sensitivity to intraocular pressure (IOP). We have shown that elevated IOP causes an early increase in levels of reactive oxygen species (ROS) in the microbead occlusion mouse model. We also detected a...
Autores principales: | Naguib, Sarah, Backstrom, Jon R., Artis, Elisabeth, Ghose, Purnima, Stahl, Amy, Hardin, Rachael, Haider, Ameer A., Ang, John, Calkins, David J., Rex, Tonia S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594672/ https://www.ncbi.nlm.nih.gov/pubmed/37875948 http://dx.doi.org/10.1186/s40478-023-01663-1 |
Ejemplares similares
-
Intraocular Sustained Release of EPO-R76E Mitigates Glaucoma Pathogenesis by Activating the NRF2/ARE Pathway
por: Naguib, Sarah, et al.
Publicado: (2023) -
Retinal oxidative stress activates the NRF2/ARE pathway: An early endogenous protective response to ocular hypertension
por: Naguib, Sarah, et al.
Publicado: (2021) -
cGMP Signaling in the Neurovascular Unit—Implications for Retinal Ganglion Cell Survival in Glaucoma
por: Haider, Ameer A., et al.
Publicado: (2022) -
Retinal ganglion cells adapt to ionic stress in experimental glaucoma
por: Boal, Andrew M., et al.
Publicado: (2023) -
Retinal Glia Promote Dorsal Root Ganglion Axon Regeneration
por: Lorber, Barbara, et al.
Publicado: (2015)