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Benchmarking algorithms for joint integration of unpaired and paired single-cell RNA-seq and ATAC-seq data
BACKGROUND: Single-cell RNA-sequencing (scRNA-seq) measures gene expression in single cells, while single-nucleus ATAC-sequencing (snATAC-seq) quantifies chromatin accessibility in single nuclei. These two data types provide complementary information for deciphering cell types and states. However, w...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594700/ https://www.ncbi.nlm.nih.gov/pubmed/37875977 http://dx.doi.org/10.1186/s13059-023-03073-x |