Benchmarking algorithms for joint integration of unpaired and paired single-cell RNA-seq and ATAC-seq data

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BACKGROUND: Single-cell RNA-sequencing (scRNA-seq) measures gene expression in single cells, while single-nucleus ATAC-sequencing (snATAC-seq) quantifies chromatin accessibility in single nuclei. These two data types provide complementary information for deciphering cell types and states. However, w...

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Detalles Bibliográficos
Autores principales: Lee, Michelle Y. Y., Kaestner, Klaus H., Li, Mingyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594700/
https://www.ncbi.nlm.nih.gov/pubmed/37875977
http://dx.doi.org/10.1186/s13059-023-03073-x

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