Distinct effects of Fgf7 and Fgf10 on the terminal differentiation of murine bladder urothelium revealed using an organoid culture system

BACKGROUND: Dysregulation of the terminal differentiation of bladder urothelium is associated with the pathogenesis of urinary tract disorders. Fibroblast growth factor (Fgf)7 and Fgf10 stimulate urothelial proliferation; however, their roles in cellular differentiation remain unclear. In this study...

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Detalles Bibliográficos
Autores principales: Suda, Kazuto, Matsumoto, Yuka, Ochi, Takanori, Koga, Hiroyuki, Hattori, Nobutaka, Yamataka, Atsuyuki, Nakamura, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594814/
https://www.ncbi.nlm.nih.gov/pubmed/37875848
http://dx.doi.org/10.1186/s12894-023-01338-y

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