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Psoralen synergizes with exosome-loaded SPC25 to alleviate senescence of nucleus pulposus cells in intervertebral disc degeneration

OBJECTIVE: To explore the mechanism of psoralen synergized with exosomes (exos)-loaded SPC25 on nucleus pulposus (NP) cell senescence in intervertebral disc degeneration (IVDD). METHODS: IVDD cellular models were established on NP cells by tert-butyl hydroperoxide (TBHP) induction, followed by the t...

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Detalles Bibliográficos
Autores principales:	Yang, Lei, Li, Zhaoyong, Zhang, Chao, Li, Shuofu, Chen, Long, Yang, Shaofeng, Guo, Yantao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594823/ https://www.ncbi.nlm.nih.gov/pubmed/37872583 http://dx.doi.org/10.1186/s13018-023-04085-w

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