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A cluster of X-linked miRNAs are de-repressed with age in mouse liver and target growth hormone signaling

Growth hormone (GH) signaling influences lifespan in a wide variety of mammalian species. We previously reported that a cluster of miRNAs located on the X-chromosome are de-repressed with age in male mouse liver, and a subset, the mir-465 family, can directly attenuate expression of the growth hormo...

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Detalles Bibliográficos
Autores principales: Petrashen, Anna P., Lin, Yufei, Kun, Bianca, Kreiling, Jill A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594992/
https://www.ncbi.nlm.nih.gov/pubmed/37881503
http://dx.doi.org/10.3389/fragi.2023.1261121

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