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A cluster of X-linked miRNAs are de-repressed with age in mouse liver and target growth hormone signaling
Growth hormone (GH) signaling influences lifespan in a wide variety of mammalian species. We previously reported that a cluster of miRNAs located on the X-chromosome are de-repressed with age in male mouse liver, and a subset, the mir-465 family, can directly attenuate expression of the growth hormo...
Autores principales: | Petrashen, Anna P., Lin, Yufei, Kun, Bianca, Kreiling, Jill A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10594992/ https://www.ncbi.nlm.nih.gov/pubmed/37881503 http://dx.doi.org/10.3389/fragi.2023.1261121 |
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