Construction of pseudorabies virus variant attenuated vaccine: codon deoptimization of US3 and UL56 genes based on PRV gE/TK deletion strain

Since 2011, pseudorabies based on the pseudorabies virus (PRV) variant has emerged as a serious health issue in pig farms in China. The PRV gE/TK or gE/gI/TK deletion strains protect against emerging PRV variants. However, these variants may cause lethal infections in newborn piglets without PRV ant...

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Detalles Bibliográficos
Autores principales: Xu, Mengwei, Zhu, Laixu, Ge, Aimin, Liu, Yamei, Chen, Saisai, Wei, Ziwen, Zheng, Yating, Tong, Ling, Wang, Zhisheng, Fei, Rongmei, Wang, Jichun, Zhang, Chuanjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10595036/
https://www.ncbi.nlm.nih.gov/pubmed/37881250
http://dx.doi.org/10.3389/fmicb.2023.1248573

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