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Eccrine Poroma with Concurrent Basal Cell Carcinoma: A Rare Combination
Eccrine poroma (EP) is a benign skin appendicular tumor that differentiates into the terminal sweat duct and is often differentiated from basal cell carcinoma (BCC) and seborrheic keratosis. This report describes a 58-year-old woman who presented with left occipital plaque. Histopathological analysi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10595198/ https://www.ncbi.nlm.nih.gov/pubmed/37881203 http://dx.doi.org/10.2147/CCID.S428611 |
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author | Shao, Xingran Dong, Yaqi Liu, Han Wei, Jiao Xiong, Xiao |
author_facet | Shao, Xingran Dong, Yaqi Liu, Han Wei, Jiao Xiong, Xiao |
author_sort | Shao, Xingran |
collection | PubMed |
description | Eccrine poroma (EP) is a benign skin appendicular tumor that differentiates into the terminal sweat duct and is often differentiated from basal cell carcinoma (BCC) and seborrheic keratosis. This report describes a 58-year-old woman who presented with left occipital plaque. Histopathological analysis showed that the tumor cells were located in the lower part of the epidermis. The tumor cells were cuboidal or circular basal-like cells of the same size. The surrounding cells were not arranged in a palisade shape. Scattered tumor clusters composed of basal-like cells were also seen in the dermis, staining basophilic, and the surrounding cells were arranged in a palisade pattern. Immunohistochemistry showed that BerEP4, epithelial membrane antigen EMA, carcinoembryonic antigen CEA, Bcl-2, CD10, CK7 were positive, AR, PAS were negative. According to the pathological examination and immunohistochemical results, a case of eccrine poroma with concurrent basal cell carcinoma was diagnosed. |
format | Online Article Text |
id | pubmed-10595198 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-105951982023-10-25 Eccrine Poroma with Concurrent Basal Cell Carcinoma: A Rare Combination Shao, Xingran Dong, Yaqi Liu, Han Wei, Jiao Xiong, Xiao Clin Cosmet Investig Dermatol Case Report Eccrine poroma (EP) is a benign skin appendicular tumor that differentiates into the terminal sweat duct and is often differentiated from basal cell carcinoma (BCC) and seborrheic keratosis. This report describes a 58-year-old woman who presented with left occipital plaque. Histopathological analysis showed that the tumor cells were located in the lower part of the epidermis. The tumor cells were cuboidal or circular basal-like cells of the same size. The surrounding cells were not arranged in a palisade shape. Scattered tumor clusters composed of basal-like cells were also seen in the dermis, staining basophilic, and the surrounding cells were arranged in a palisade pattern. Immunohistochemistry showed that BerEP4, epithelial membrane antigen EMA, carcinoembryonic antigen CEA, Bcl-2, CD10, CK7 were positive, AR, PAS were negative. According to the pathological examination and immunohistochemical results, a case of eccrine poroma with concurrent basal cell carcinoma was diagnosed. Dove 2023-10-20 /pmc/articles/PMC10595198/ /pubmed/37881203 http://dx.doi.org/10.2147/CCID.S428611 Text en © 2023 Shao et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Case Report Shao, Xingran Dong, Yaqi Liu, Han Wei, Jiao Xiong, Xiao Eccrine Poroma with Concurrent Basal Cell Carcinoma: A Rare Combination |
title | Eccrine Poroma with Concurrent Basal Cell Carcinoma: A Rare Combination |
title_full | Eccrine Poroma with Concurrent Basal Cell Carcinoma: A Rare Combination |
title_fullStr | Eccrine Poroma with Concurrent Basal Cell Carcinoma: A Rare Combination |
title_full_unstemmed | Eccrine Poroma with Concurrent Basal Cell Carcinoma: A Rare Combination |
title_short | Eccrine Poroma with Concurrent Basal Cell Carcinoma: A Rare Combination |
title_sort | eccrine poroma with concurrent basal cell carcinoma: a rare combination |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10595198/ https://www.ncbi.nlm.nih.gov/pubmed/37881203 http://dx.doi.org/10.2147/CCID.S428611 |
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