Cargando…

Urine-mediated suppression of Klebsiella pneumoniae mucoidy is counteracted by spontaneous Wzc variants altering capsule chain length

Klebsiella pneumoniae is a hospital-associated pathogen primarily causing urinary tract infections (UTIs), pneumonia, and septicemia. Two challenging lineages include the hypervirulent strains, causing invasive community-acquired infections, and the carbapenem-resistant classical strains, most frequ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khadka, Saroj, Ring, Brooke E., Walker, Ryan S., Krzeminski, Lindsey R., Pariseau, Drew A., Hathaway, Matthew, Mobley, Harry L. T., Mike, Laura A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597399/ https://www.ncbi.nlm.nih.gov/pubmed/37610214 http://dx.doi.org/10.1128/msphere.00288-23

Ejemplares similares

The molecular basis of regulation of bacterial capsule assembly by Wzc
por: Yang, Yun, et al.
Publicado: (2021)

Capsular Types of Klebsiella pneumoniae Revisited by wzc Sequencing
por: Pan, Yi-Jiun, et al.
Publicado: (2013)

Phage Selective Pressure Reduces Virulence of Hypervirulent Klebsiella pneumoniae Through Mutation of the wzc Gene
por: Song, Lingjie, et al.
Publicado: (2021)

Hypermucoviscosity Regulator RmpD Interacts with Wzc and Controls Capsular Polysaccharide Chain Length
por: Ovchinnikova, Olga G., et al.
Publicado: (2023)

Mucoidy, a general mechanism for maintaining lytic phage in populations of bacteria
por: Chaudhry, Waqas, et al.
Publicado: (2020)

Truncation of type IV pilin induces mucoidy in Pseudomonas aeruginosa strain PAO579
por: Ryan Withers, T, et al.
Publicado: (2013)

A Pseudomonas fluorescens type 6 secretion system is related to mucoidy, motility and bacterial competition
por: Decoin, Victorien, et al.
Publicado: (2015)

An ATPase with a twist: A unique mechanism underlies the activity of the bacterial tyrosine kinase, Wzc
por: Hajredini, Fatlum, et al.
Publicado: (2021)

Structural basis for the recognition of the bacterial tyrosine kinase Wzc by its cognate tyrosine phosphatase Wzb
por: Alphonse, Sébastien, et al.
Publicado: (2022)

Mucoidy, Quorum Sensing, Mismatch Repair and Antibiotic Resistance in Pseudomonas aeruginosa from Cystic Fibrosis Chronic Airways Infections
por: Feliziani, Sofía, et al.
Publicado: (2010)

A systematic analysis of hypermucoviscosity and capsule reveals distinct and overlapping genes that impact Klebsiella pneumoniae fitness
por: Mike, Laura A., et al.
Publicado: (2021)

Klebsiella pneumoniae infection biology: living to counteract host defences
por: Bengoechea, José A, et al.
Publicado: (2018)

The role of the tyrosine kinase Wzc (Sll0923) and the phosphatase Wzb (Slr0328) in the production of extracellular polymeric substances (EPS) by Synechocystis PCC 6803
por: Pereira, Sara B., et al.
Publicado: (2019)

Klebsiella pneumoniae capsule polysaccharide as a target for therapeutics and vaccines
por: Opoku-Temeng, Clement, et al.
Publicado: (2019)

Nutrient conditions are primary drivers of bacterial capsule maintenance in Klebsiella
por: Buffet, Amandine, et al.
Publicado: (2021)

Spectrofluorimetric and Spectrophotometric Determination of Pregabalin in Capsules and Urine Samples
por: Shaalan, Rasha Abdel-Aziz
Publicado: (2010)

The Klebsiella pneumoniae ter Operon Enhances Stress Tolerance
por: Mason, Sophia, et al.
Publicado: (2023)

The Capsule Regulatory Network of Klebsiella pneumoniae Defined by density-TraDISort
por: Dorman, Matthew J., et al.
Publicado: (2018)

Identification of Klebsiella capsule synthesis loci from whole genome data
por: Wyres, Kelly L., et al.
Publicado: (2016)

Researchers wrangle petabytes of data storage with NAS, tape
por: Pariseau, Beth
Publicado: (2007)

Kaptive Web: User-Friendly Capsule and Lipopolysaccharide Serotype Prediction for Klebsiella Genomes
por: Wick, Ryan R., et al.
Publicado: (2018)

Deciphering the role of the capsule of Klebsiella pneumoniae during pathogenesis: A cautionary tale
por: Rendueles, Olaya
Publicado: (2020)

Defining principles that influence antimicrobial peptide activity against capsulated Klebsiella pneumoniae
por: Fleeman, Renee M., et al.
Publicado: (2020)

Mechanistic Insights into the Capsule-Targeting Depolymerase from a Klebsiella pneumoniae Bacteriophage
por: Dunstan, Rhys A., et al.
Publicado: (2021)

The Capsule Increases Susceptibility to Last-Resort Polymyxins, but Not to Other Antibiotics, in Klebsiella pneumoniae
por: D’Angelo, Francesca, et al.
Publicado: (2023)

Engineered reporter phages for detection of Escherichia coli, Enterococcus, and Klebsiella in urine
por: Meile, Susanne, et al.
Publicado: (2023)

Extensively Drug-Resistant Klebsiella pneumoniae Counteracts Fitness and Virulence Costs That Accompanied Ceftazidime-Avibactam Resistance Acquisition
por: Eger, Elias, et al.
Publicado: (2022)

A Klebsiella pneumoniae Regulatory Mutant Has Reduced Capsule Expression but Retains Hypermucoviscosity
por: Walker, Kimberly A., et al.
Publicado: (2019)

Development of Klebsiella pneumoniae Capsule Polysaccharide-Conjugated Vaccine Candidates Using Phage Depolymerases
por: Lin, Tzu-Lung, et al.
Publicado: (2022)

Engineering the Modular Receptor-Binding Proteins of Klebsiella Phages Switches Their Capsule Serotype Specificity
por: Latka, Agnieszka, et al.
Publicado: (2021)

LPS O Antigen Plays a Key Role in Klebsiella pneumoniae Capsule Retention
por: Singh, Shweta, et al.
Publicado: (2022)

Capsule type defines the capability of Klebsiella pneumoniae in evading Kupffer cell capture in the liver
por: Huang, Xueting, et al.
Publicado: (2022)

Phenotypic Heterogeneity in Expression of the K1 Polysaccharide Capsule of Uropathogenic Escherichia coli and Downregulation of the Capsule Genes during Growth in Urine
por: King, Jane E., et al.
Publicado: (2015)

Effects of Bailing capsule on diabetic nephropathy based on UPLC-MS urine metabolomics
por: Xu, Junnan, et al.
Publicado: (2019)

Identification of three podoviruses infecting Klebsiella encoding capsule depolymerases that digest specific capsular types
por: Pan, Yi‐Jiun, et al.
Publicado: (2019)

A Klebsiella variicola Plasmid Confers Hypermucoviscosity-Like Phenotype and Alters Capsule Production and Virulence
por: Rodríguez-Medina, Nadia, et al.
Publicado: (2020)

Kaptive 2.0: updated capsule and lipopolysaccharide locus typing for the Klebsiella pneumoniae species complex
por: Lam, Margaret M. C., et al.
Publicado: (2022)

Streptococcus pneumoniae capsule determines disease severity in experimental pneumococcal meningitis
por: Hathaway, Lucy J., et al.
Publicado: (2016)

Pneumococcal serotype determines growth and capsule size in human cerebrospinal fluid
por: Müller, Annelies, et al.
Publicado: (2020)

Capsule Production and Glucose Metabolism Dictate Fitness during Serratia marcescens Bacteremia
por: Anderson, Mark T., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ahv43t301unird6uhpv5re6knb