Intracellular replication of Pseudomonas aeruginosa in epithelial cells requires suppression of the caspase-4 inflammasome

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Pathogenesis of Pseudomonas aeruginosa infections can include bacterial survival inside epithelial cells. Previously, we showed that this involves multiple roles played by the type three secretion system (T3SS), and specifically the effector ExoS. This includes ExoS-dependent inhibition of a lytic h...

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Detalles Bibliográficos
Autores principales: Kroken, Abby R., Klein, Keith A., Mitchell, Patrick S., Nieto, Vincent, Jedel, Eric J., Evans, David J., Fleiszig, Suzanne M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597407/
https://www.ncbi.nlm.nih.gov/pubmed/37589460
http://dx.doi.org/10.1128/msphere.00351-23
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