The QseB response regulator imparts tolerance to positively charged antibiotics by controlling metabolism and minor changes to LPS

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The modification of lipopolysaccharide (LPS) in Escherichia coli and Salmonella spp. is primarily controlled by the two-component system PmrAB. LPS modification allows bacteria to avoid killing by positively charged antibiotics like polymyxin B (PMB). We previously demonstrated that in uropathogenic...

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Detalles Bibliográficos
Autores principales: Hurst, Melanie N., Beebout, Connor J., Hollingsworth, Alexis, Guckes, Kirsten R., Purcell, Alexandria, Bermudez, Tomas A., Williams, Diamond, Reasoner, Seth A., Trent, M. Stephen, Hadjifrangiskou, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597456/
https://www.ncbi.nlm.nih.gov/pubmed/37676915
http://dx.doi.org/10.1128/msphere.00059-23
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