Cargando…

Mitochondrial pannexin1 controls cardiac sensitivity to ischaemia/reperfusion injury

AIMS: No effective therapy is available in clinics to protect the heart from ischaemia/reperfusion (I/R) injury. Endothelial cells are activated after I/R, which may drive the inflammatory response by releasing ATP through pannexin1 (Panx1) channels. Here, we investigated the role of Panx1 in cardia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rusiecka, Olga M, Molica, Filippo, Nielsen, Morten S, Tollance, Axel, Morel, Sandrine, Frieden, Maud, Chanson, Marc, Boengler, Kerstin, Kwak, Brenda R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597630/ https://www.ncbi.nlm.nih.gov/pubmed/37556386 http://dx.doi.org/10.1093/cvr/cvad120

Ejemplares similares

Pannexin1 channels—a potential therapeutic target in inflammation
por: Rusiecka, Olga M., et al.
Publicado: (2022)

A Genetic Polymorphism in the Pannexin1 Gene Predisposes for The Development of Endothelial Dysfunction with Increasing BMI
por: Molica, Filippo, et al.
Publicado: (2020)

Lymphatic Connexins and Pannexins in Health and Disease
por: Ehrlich, Avigail, et al.
Publicado: (2021)

Pannexin1 links lymphatic function to lipid metabolism and atherosclerosis
por: Molica, Filippo, et al.
Publicado: (2017)

Pannexin- and Connexin-Mediated Intercellular Communication in Platelet Function
por: Molica, Filippo, et al.
Publicado: (2017)

Connexins and Pannexins in Vascular Function and Disease
por: Molica, Filippo, et al.
Publicado: (2018)

Activation and Migration of Human Skeletal Muscle Stem Cells In Vitro Differently Rely on Calcium Signals
por: Tollance, Axel, et al.
Publicado: (2022)

Mitochondrial mechanisms and therapeutics in ischaemia reperfusion injury
por: Martin, Jack L., et al.
Publicado: (2018)

Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion
por: Boengler, Kerstin, et al.
Publicado: (2010)

Roles of mitochondrial dynamics modulators in cardiac ischaemia/reperfusion injury
por: Maneechote, Chayodom, et al.
Publicado: (2017)

Alterations in mitochondrial protein glycosylation in myocardial ischaemia reperfusion injury
por: Feng, Xinyu, et al.
Publicado: (2023)

Intercellular Communication in Airway Epithelial Cell Regeneration: Potential Roles of Connexins and Pannexins
por: Badaoui, Mehdi, et al.
Publicado: (2023)

Melatonin has profound effects on mitochondrial dynamics in myocardial ischaemia/reperfusion
por: Dube, K., et al.
Publicado: (2019)

Mitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis
por: Wang, Peina, et al.
Publicado: (2021)

Mitochondrial and mitochondrial‐independent pathways of myocardial cell death during ischaemia and reperfusion injury
por: Davidson, Sean M., et al.
Publicado: (2020)

Pannexin 1 as a driver of inflammation and ischemia–reperfusion injury
por: Koval, Michael, et al.
Publicado: (2021)

Corticomedullary shunting after ischaemia and reperfusion in the porcine kidney?
por: Rehling, Michael, et al.
Publicado: (2022)

CXCR4 attenuates cardiomyocytes mitochondrial dysfunction to resist ischaemia-reperfusion injury
por: Cai, Wen-Feng, et al.
Publicado: (2015)

Dendritic Cell Migration Toward CCL21 Gradient Requires Functional Cx43
por: Ruez, Richard, et al.
Publicado: (2018)

Necroptosis in Hepatosteatotic Ischaemia-Reperfusion Injury
por: Baidya, Raji, et al.
Publicado: (2020)

Complement in ischaemia–reperfusion injury and transplantation
por: Howard, Mark C., et al.
Publicado: (2021)

Pannexin 1 targets mitophagy to mediate renal ischemia/reperfusion injury
por: Su, Lianjiu, et al.
Publicado: (2023)

Canonical and Non-Canonical Roles of Connexin43 in Cardioprotection
por: Rusiecka, Olga M., et al.
Publicado: (2020)

The role of mitochondrial reactive oxygen species, NO and H(2)S in ischaemia/reperfusion injury and cardioprotection
por: Andreadou, Ioanna, et al.
Publicado: (2020)

Correction to: Complement in ischaemia–reperfusion injury and transplantation
por: Howard, Mark C., et al.
Publicado: (2022)

Lack of Contribution of p66shc and Its Mitochondrial Translocation to Ischemia-Reperfusion Injury and Cardioprotection by Ischemic Preconditioning
por: Boengler, Kerstin, et al.
Publicado: (2017)

Structural apelin analogues: mitochondrial ROS inhibition and cardiometabolic protection in myocardial ischaemia reperfusion injury
por: Pisarenko, Oleg, et al.
Publicado: (2015)

Pre‐conditions for eliminating mitochondrial dysfunction and maintaining liver function after hepatic ischaemia reperfusion
por: Hu, Chenxia, et al.
Publicado: (2017)

Browning of White Adipose Tissue as a Therapeutic Tool in the Fight against Atherosclerosis
por: Roth, Christel L., et al.
Publicado: (2021)

Human monocytes subjected to ischaemia/reperfusion inhibit angiogenesis and wound healing in vitro
por: Hummitzsch, Lars, et al.
Publicado: (2020)

The cardioprotective potential of valsartan in myocardial ischaemia reperfusion injury
por: Hadi, Najah R., et al.
Publicado: (2015)

The effects of ischaemic conditioning on lung ischaemia–reperfusion injury
por: Vlastos, Dimitrios, et al.
Publicado: (2022)

Notch1 protects against myocardial ischaemia‐reperfusion injury via regulating mitochondrial fusion and function
por: Dai, Shao-hua, et al.
Publicado: (2020)

Nanobody-based pannexin1 channel inhibitors reduce inflammation in acute liver injury
por: Van Campenhout, Raf, et al.
Publicado: (2023)

The pannexins: past and present
por: Bond, Stephen R., et al.
Publicado: (2014)

Connexin 43 impacts on mitochondrial potassium uptake
por: Boengler, Kerstin, et al.
Publicado: (2013)

N-Glycosylation Regulates Pannexin 2 Localization but Is Not Required for Interacting with Pannexin 1
por: Sanchez-Pupo, Rafael E., et al.
Publicado: (2018)

The dysregulation of metabolic pathways and induction of the pentose phosphate pathway in renal ischaemia–reperfusion injury
por: Scantlebery, Angelique ML, et al.
Publicado: (2021)

Mitochondrial import of PKCε is mediated by HSP90: a role in cardioprotection from ischaemia and reperfusion injury
por: Budas, Grant R., et al.
Publicado: (2010)

Hydralazine protects the heart against acute ischaemia/reperfusion injury by inhibiting Drp1-mediated mitochondrial fission
por: Kalkhoran, Siavash Beikoghli, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qkoo1op45g0crg9c6j1iv9psdl