TP53-PTEN-NF1 depletion in human brain organoids produces a glioma phenotype in vitro

Glioblastoma (GBM) is fatal and the study of therapeutic resistance, disease progression, and drug discovery in GBM or glioma stem cells is often hindered by limited resources. This limitation slows down progress in both drug discovery and patient survival. Here we present a genetically engineered h...

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Detalles Bibliográficos
Autores principales: Singh, Sanjay K., Wang, Yan, Habib, Ahmed, Priyadarshini, Mamindla, Kodavali, Chowdari V., Chen, Apeng, Ma, Wencai, Wang, Jing, Hameed, N. U. Farrukh, Hu, Baoli, Fuller, Gregory N., Kulich, Scott M., Amankulor, Nduka, Colen, Rivka R., Edwards, Lincoln A., Zinn, Pascal O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597663/
https://www.ncbi.nlm.nih.gov/pubmed/37881491
http://dx.doi.org/10.3389/fonc.2023.1279806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597663/
https://www.ncbi.nlm.nih.gov/pubmed/37881491
http://dx.doi.org/10.3389/fonc.2023.1279806

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