Cargando…

Quercetin: A promising drug candidate against the potential SARS-CoV-2-Spike mutants with high viral infectivity

The emergence of SARS-CoV-2-Spike mutants not only enhances viral infectivity but also lead to treatment failure. Gaining a comprehensive understanding of the molecular binding mode between the mutant SARS-CoV-2-Spike and human ACE2 receptor is crucial for therapeutic development against this virus....

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Boyu, Fang, Senbiao, Wang, Liangjiao, Pan, Zhanyu, Li, Min, Liu, Liren
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Research Network of Computational and Structural Biotechnology 2023
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597750/ https://www.ncbi.nlm.nih.gov/pubmed/37881508 http://dx.doi.org/10.1016/j.csbj.2023.10.029

Ejemplares similares

Chinese herbal compounds against SARS-CoV-2: Puerarin and quercetin impair the binding of viral S-protein to ACE2 receptor
por: Pan, Boyu, et al.
Publicado: (2020)

Collaborative effects of 2019-nCoV-Spike mutants on viral infectivity
por: Fang, Senbiao, et al.
Publicado: (2023)

Cinnamomi Ramulus inhibits the growth of colon cancer cells via Akt/ERK signaling pathways
por: Pan, Boyu, et al.
Publicado: (2022)

Potential Prospective Biomarkers for Non-small Cell Lung Cancer: Mini-Chromosome Maintenance Proteins
por: Huang, Chen, et al.
Publicado: (2021)

A Mechanism of Action Study on Danggui Sini Decoction to Discover Its Therapeutic Effect on Gastric Cancer
por: Pan, Boyu, et al.
Publicado: (2021)

TACE antagonists blocking ACE2 shedding caused by the spike protein of SARS-CoV are candidate antiviral compounds
por: Haga, Shiori, et al.
Publicado: (2010)

SARS‐CoV‐2 viral spike G614 mutation exhibits higher case fatality rate
por: Becerra‐Flores, Manuel, et al.
Publicado: (2020)

Quercetin, a Promising Clinical Candidate for The Prevention of Contrast-Induced Nephropathy
por: Vicente-Vicente, Laura, et al.
Publicado: (2019)

Integrated network pharmacology and serum metabolomics approach deciphers the anti-colon cancer mechanisms of Huangqi Guizhi Wuwu Decoction
por: Pan, Boyu, et al.
Publicado: (2022)

Structural analysis of spike proteins from SARS-CoV-2 variants of concern highlighting their functional alterations
por: Solanki, Kundan, et al.
Publicado: (2022)

The Spike Mutants Website: A Worldwide Used Resource against SARS-CoV-2
por: Romeo, Isabella, et al.
Publicado: (2022)

Presence of antibodies against SARS-CoV-2 spike protein in bovine whey IgG enriched fraction
por: Oshiro, Satoshi, et al.
Publicado: (2021)

Antibodies against spike protein of SARS-CoV-2 variants in bovine whey IgG enriched fraction
por: Oshiro, Satoshi, et al.
Publicado: (2022)

SARS-CoV-2 variants – Evolution, spike protein, and vaccines
por: Chen, Kai-Wei K., et al.
Publicado: (2022)

Emergence of SARS‐CoV‐2 spike protein at the vaccination site
por: Beck, Annika, et al.
Publicado: (2023)

Spike-directed vaccination elicits robust spike-specific T-cell response, including to mutant strains
por: Stanojevic, Maja, et al.
Publicado: (2022)

Interaction of Epigallocatechin Gallate and Quercetin with Spike Glycoprotein (S-Glycoprotein) of SARS-CoV-2: In Silico Study
por: Alavi, Mehran, et al.
Publicado: (2022)

Altered hACE2 binding affinity and S1/S2 cleavage efficiency of SARS-CoV-2 spike protein mutants affect viral cell entry
por: Wang, Ke, et al.
Publicado: (2023)

LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein
por: Shilts, Jarrod, et al.
Publicado: (2023)

A SARS-CoV-2 mutant from B.1.258 lineage with ∆H69/∆V70 deletion in the Spike protein circulating in Central Europe in the fall 2020
por: Brejová, Broňa, et al.
Publicado: (2021)

Laser-facilitated epicutaneous immunization of mice with SARS-CoV-2 spike protein induces antibodies inhibiting spike/ACE2 binding
por: Scheiblhofer, Sandra, et al.
Publicado: (2021)

Paxlovid: A promising drug for the challenging treatment of SARS-COV-2 in the pandemic era
por: Niraj, Niraj, et al.
Publicado: (2022)

Human post‐infection serological response to the spike and nucleocapsid proteins of SARS‐CoV‐2
por: Xiao, Cheng, et al.
Publicado: (2020)

D614G Spike Mutation Increases SARS CoV-2 Susceptibility to Neutralization
por: Weissman, Drew, et al.
Publicado: (2021)

Antibody engineering improves neutralization activity against K417 spike mutant SARS-CoV-2 variants
por: Li, Lili, et al.
Publicado: (2022)

Mice Immunized with the Vaccine Candidate HexaPro Spike Produce Neutralizing Antibodies against SARS-CoV-2
por: Seephetdee, Chotiwat, et al.
Publicado: (2021)

A comprehensive review on promising anti-viral therapeutic candidates identified against main protease from SARS-CoV-2 through various computational methods
por: Singh, Ekampreet, et al.
Publicado: (2020)

The Architecture of Inactivated SARS-CoV-2 with Postfusion Spikes Revealed by Cryo-EM and Cryo-ET
por: Liu, Chuang, et al.
Publicado: (2020)

ACE2-cytomimetic particles restrict SARS-Cov-2 spike protein binding to cellular targets
por: Strong, Thomas A., et al.
Publicado: (2021)

Penta-peptide ATN-161 based neutralization mechanism of SARS-CoV-2 spike protein
por: Rabbani, Gulam, et al.
Publicado: (2021)

Immunity evasion: consequence of the N501Y mutation of the SARS-CoV-2 spike glycoprotein
por: Uzoeto, Henrietta Onyinye, et al.
Publicado: (2022)

SARS-CoV-2 recombinant spike protein induces cell apoptosis in rat taste buds
por: Yamamoto, Toru, et al.
Publicado: (2023)

Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein
por: Javanmardi, Kamyab, et al.
Publicado: (2022)

In silico discovery of 3 novel quercetin derivatives against papain-like protease, spike protein, and 3C-like protease of SARS-CoV-2
por: Bhattacharya, Kunal, et al.
Publicado: (2022)

Evaluation of SARS-CoV-2 viral RNA in fecal samples
por: Mesoraca, Alvaro, et al.
Publicado: (2020)

A Novel Vaccine Employing Non-Replicating Rabies Virus Expressing Chimeric SARS-CoV-2 Spike Protein Domains: Functional Inhibition of Viral/Nicotinic Acetylcholine Receptor Complexes
por: Stefano, Michelle L., et al.
Publicado: (2020)

Immunogenicity of candidate SARS-CoV-2 DNA vaccines based on the spike protein
por: Lim, Heeji, et al.
Publicado: (2022)

Silibinin as potential tool against SARS‐Cov‐2: In silico spike receptor‐binding domain and main protease molecular docking analysis, and in vitro endothelial protective effects
por: Speciale, Antonio, et al.
Publicado: (2021)

Correlation of dried blood spots and plasma for quantification of Immunoglobulin (IgG) against Receptor binding domain and full length spike protein of SARS-CoV-2
por: Kwatra, Gaurav, et al.
Publicado: (2022)

Molecular recognition of SARS-CoV-2 spike protein with three essential partners: exploring possible immune escape mechanisms of viral mutants
por: Cheng, Yan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_fr6vft85r2sdll225ton2up5bm