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PAPγ associates with PAXT nuclear exosome to control the abundance of PROMPT ncRNAs
Pervasive transcription of the human genome generates an abundance of RNAs that must be processed and degraded. The nuclear RNA exosome is the main RNA degradation machinery in the nucleus. However, nuclear exosome must be recruited to its substrates by targeting complexes, such as NEXT or PAXT. By...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598014/ https://www.ncbi.nlm.nih.gov/pubmed/37875486 http://dx.doi.org/10.1038/s41467-023-42620-9 |