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Exogenous H(2)S initiating Nrf2/GPx4/GSH pathway through promoting Syvn1-Keap1 interaction in diabetic hearts

Excessive ROS accumulation contributes to cardiac injury in type 2 diabetes mellitus. Hydrogen sulfide (H(2)S) is a vital endogenous gasotransmitter to alleviate cardiac damage in diabetic cardiomyopathy (DCM). However, the underlying mechanisms remain unclear. In this study, we investigated the eff...

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Detalles Bibliográficos
Autores principales:	Wang, Mengyi, Tang, Jingyuan, Zhang, Shiwu, Pang, Kemiao, Zhao, Yajun, Liu, Ning, Huang, Jiayi, Kang, Jiaxin, Dong, Shiyun, Li, Hongxia, Tian, Zhen, Duan, Binhong, Lu, Fanghao, Zhang, Weihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598017/ https://www.ncbi.nlm.nih.gov/pubmed/37875467 http://dx.doi.org/10.1038/s41420-023-01690-w

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