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Our house believes that: The clipped lymph node is the true sentinel node after neoadjuvant chemotherapy in N+ patients()

Axillary staging is an important prognostic factor in breast cancer, being sentinel lymph node biopsy (SLNB) the gold standard staging method in early stages. However, in clinically node positive (cN+) patients who converted to clinically node-negative (cN0) after primary systemic therapy (PST) the...

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Detalles Bibliográficos
Autores principales: Acea-Nebril, Benigno, García-Novoa, Alejandra, Bouzón Alejandro, Alberto, Díaz Carballada, Carlota, Conde Iglesias, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598034/
https://www.ncbi.nlm.nih.gov/pubmed/37857128
http://dx.doi.org/10.1016/j.breast.2023.103592
Descripción
Sumario:Axillary staging is an important prognostic factor in breast cancer, being sentinel lymph node biopsy (SLNB) the gold standard staging method in early stages. However, in clinically node positive (cN+) patients who converted to clinically node-negative (cN0) after primary systemic therapy (PST) the axillary staging method during surgery remains controversial. There are at least three validated methods: SLNB, targeted axillary dissection (TAD) and marking axillary nodes with radioactive iodine seeds (MARI) procedure. Our house believe that the biopsied and clipped lymph node could predict response to systemic treatment.