Escherichia coli Promotes Endothelial to Mesenchymal Transformation of Liver Sinusoidal Endothelial Cells and Exacerbates Nonalcoholic Fatty Liver Disease Via Its Flagellin

BACKGROUND＆AIMS: Gut bacteria translocate into the liver through a disrupted gut vascular barrier, which is an early and common event in the development of nonalcoholic fatty liver disease (NAFLD). Liver sinusoidal endothelial cells (LSECs) are directly exposed to translocated gut microbiota in port...

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Detalles Bibliográficos
Autores principales: Shen, Bo, Gu, Tianyi, Shen, Zhenyang, Zhou, Cui, Guo, Yuecheng, Wang, Junjun, Li, Binghang, Xu, Xianjun, Li, Fei, Zhang, Qidi, Cai, Xiaobo, Dong, Hui, Lu, Lungen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598062/
https://www.ncbi.nlm.nih.gov/pubmed/37572735
http://dx.doi.org/10.1016/j.jcmgh.2023.08.001

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