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Comparison of two lab-scale protocols for enhanced mRNA-based CAR-T cell generation and functionality

Process development for transferring lab-scale research workflows to automated manufacturing procedures is critical for chimeric antigen receptor (CAR)-T cell therapies. Therefore, the key factor for cell viability, expansion, modification, and functionality is the optimal combination of medium and...

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Detalles Bibliográficos
Autores principales:	von Auw, Nadine, Serfling, Robert, Kitte, Reni, Hilger, Nadja, Zhang, Chengkang, Gebhardt, Clara, Duenkel, Anna, Franz, Paul, Koehl, Ulrike, Fricke, Stephan, Tretbar, U. Sandy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10598065/ https://www.ncbi.nlm.nih.gov/pubmed/37875523 http://dx.doi.org/10.1038/s41598-023-45197-x

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